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Independent phenotypic plasticity axes define distinct obesity sub-types.
Yang CH, Fagnocchi L, Apostle S, Wegert V, Casaní-Galdón S, Landgraf K, Panzeri I, Dror E, Heyne S, Wörpel T, Chandler DP, Lu D, Yang T, Gibbons E, Guerreiro R, Bras J, Thomasen M, Grunnet LG, Vaag AA, Gillberg L, Grundberg E, Conesa A, Körner A; PERMUTE; Pospisilik JA. Yang CH, et al. Among authors: pospisilik ja. Nat Metab. 2022 Sep;4(9):1150-1165. doi: 10.1038/s42255-022-00629-2. Epub 2022 Sep 12. Nat Metab. 2022. PMID: 36097183 Free PMC article.
RELACS nuclei barcoding enables high-throughput ChIP-seq.
Arrigoni L, Al-Hasani H, Ramírez F, Panzeri I, Ryan DP, Santacruz D, Kress N, Pospisilik JA, Bönisch U, Manke T. Arrigoni L, et al. Among authors: pospisilik ja. Commun Biol. 2018 Dec 5;1:214. doi: 10.1038/s42003-018-0219-z. eCollection 2018. Commun Biol. 2018. PMID: 30534606 Free PMC article.
Bridging epigenomics and complex disease: the basics.
Teperino R, Lempradl A, Pospisilik JA. Teperino R, et al. Among authors: pospisilik ja. Cell Mol Life Sci. 2013 May;70(9):1609-21. doi: 10.1007/s00018-013-1299-z. Epub 2013 Mar 6. Cell Mol Life Sci. 2013. PMID: 23463237 Free PMC article. Review.
The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes.
Lu TT, Heyne S, Dror E, Casas E, Leonhardt L, Boenke T, Yang CH, Sagar, Arrigoni L, Dalgaard K, Teperino R, Enders L, Selvaraj M, Ruf M, Raja SJ, Xie H, Boenisch U, Orkin SH, Lynn FC, Hoffman BG, Grün D, Vavouri T, Lempradl AM, Pospisilik JA. Lu TT, et al. Among authors: pospisilik ja. Cell Metab. 2018 Jun 5;27(6):1294-1308.e7. doi: 10.1016/j.cmet.2018.04.013. Epub 2018 May 10. Cell Metab. 2018. PMID: 29754954 Free PMC article.
Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity.
Dalgaard K, Landgraf K, Heyne S, Lempradl A, Longinotto J, Gossens K, Ruf M, Orthofer M, Strogantsev R, Selvaraj M, Lu TT, Casas E, Teperino R, Surani MA, Zvetkova I, Rimmington D, Tung YC, Lam B, Larder R, Yeo GS, O'Rahilly S, Vavouri T, Whitelaw E, Penninger JM, Jenuwein T, Cheung CL, Ferguson-Smith AC, Coll AP, Körner A, Pospisilik JA. Dalgaard K, et al. Among authors: pospisilik ja. Cell. 2016 Jan 28;164(3):353-64. doi: 10.1016/j.cell.2015.12.025. Cell. 2016. PMID: 26824653 Free PMC article.
CRUP: a comprehensive framework to predict condition-specific regulatory units.
Ramisch A, Heinrich V, Glaser LV, Fuchs A, Yang X, Benner P, Schöpflin R, Li N, Kinkley S, Römer-Hillmann A, Longinotto J, Heyne S, Czepukojc B, Kessler SM, Kiemer AK, Cadenas C, Arrigoni L, Gasparoni N, Manke T, Pap T, Pospisilik JA, Hengstler J, Walter J, Meijsing SH, Chung HR, Vingron M. Ramisch A, et al. Among authors: pospisilik ja. Genome Biol. 2019 Nov 8;20(1):227. doi: 10.1186/s13059-019-1860-7. Genome Biol. 2019. PMID: 31699133 Free PMC article.
Paternal diet defines offspring chromatin state and intergenerational obesity.
Öst A, Lempradl A, Casas E, Weigert M, Tiko T, Deniz M, Pantano L, Boenisch U, Itskov PM, Stoeckius M, Ruf M, Rajewsky N, Reuter G, Iovino N, Ribeiro C, Alenius M, Heyne S, Vavouri T, Pospisilik JA. Öst A, et al. Among authors: pospisilik ja. Cell. 2014 Dec 4;159(6):1352-64. doi: 10.1016/j.cell.2014.11.005. Cell. 2014. PMID: 25480298 Free article.
88 results