Fiedler D - Search Results

1

Versatile signaling mechanisms of inositol pyrophosphates.

Nguyen Trung M, Furkert D, Fiedler D. Nguyen Trung M, et al. Among authors: fiedler d. Curr Opin Chem Biol. 2022 Oct;70:102177. doi: 10.1016/j.cbpa.2022.102177. Epub 2022 Jun 30. Curr Opin Chem Biol. 2022. PMID: 35780751 Free article. Review.

2

Chemical tools for interrogating inositol pyrophosphate structure and function.

Brown NW, Marmelstein AM, Fiedler D. Brown NW, et al. Among authors: fiedler d. Chem Soc Rev. 2016 Nov 7;45(22):6311-6326. doi: 10.1039/c6cs00193a. Chem Soc Rev. 2016. PMID: 27462803 Review.

3

Inositol polyphosphates intersect with signaling and metabolic networks via two distinct mechanisms.

Wu M, Chong LS, Perlman DH, Resnick AC, Fiedler D. Wu M, et al. Among authors: fiedler d. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):E6757-E6765. doi: 10.1073/pnas.1606853113. Epub 2016 Oct 19. Proc Natl Acad Sci U S A. 2016. PMID: 27791083 Free PMC article.

4

Features and regulation of non-enzymatic post-translational modifications.

Harmel R, Fiedler D. Harmel R, et al. Among authors: fiedler d. Nat Chem Biol. 2018 Feb 14;14(3):244-252. doi: 10.1038/nchembio.2575. Nat Chem Biol. 2018. PMID: 29443975 Review.

5

MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.

Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW Jr, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, Moldoveanu T, York JD, Carette JE. Dovey CM, et al. Among authors: fiedler d. Mol Cell. 2018 Jun 7;70(5):936-948.e7. doi: 10.1016/j.molcel.2018.05.010. Epub 2018 Jun 7. Mol Cell. 2018. PMID: 29883610 Free PMC article.

6

Harnessing ¹³C-labeled myo-inositol to interrogate inositol phosphate messengers by NMR.

Harmel RK, Puschmann R, Nguyen Trung M, Saiardi A, Schmieder P, Fiedler D. Harmel RK, et al. Among authors: fiedler d. Chem Sci. 2019 Apr 23;10(20):5267-5274. doi: 10.1039/c9sc00151d. eCollection 2019 May 28. Chem Sci. 2019. PMID: 31191882 Free PMC article.

7

Scalable Chemoenzymatic Synthesis of Inositol Pyrophosphates.

Puschmann R, Harmel RK, Fiedler D. Puschmann R, et al. Among authors: fiedler d. Biochemistry. 2019 Sep 24;58(38):3927-3932. doi: 10.1021/acs.biochem.9b00587. Epub 2019 Sep 14. Biochemistry. 2019. PMID: 31461621

8

Control of XPR1-dependent cellular phosphate efflux by InsP₈ is an exemplar for functionally-exclusive inositol pyrophosphate signaling.

Li X, Gu C, Hostachy S, Sahu S, Wittwer C, Jessen HJ, Fiedler D, Wang H, Shears SB. Li X, et al. Among authors: fiedler d. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3568-3574. doi: 10.1073/pnas.1908830117. Epub 2020 Feb 4. Proc Natl Acad Sci U S A. 2020. PMID: 32019887 Free PMC article.

9

Delivery of myo-Inositol Hexakisphosphate to the Cell Nucleus with a Proline-Based Cell-Penetrating Peptide.

Li M, Puschmann R, Herdlitschka A, Fiedler D, Wennemers H. Li M, et al. Among authors: fiedler d. Angew Chem Int Ed Engl. 2020 Sep 1;59(36):15586-15589. doi: 10.1002/anie.202006770. Epub 2020 Jul 21. Angew Chem Int Ed Engl. 2020. PMID: 32558101

10

Analysis of metabolically labeled inositol phosphate messengers by NMR.

Puschmann R, Harmel RK, Fiedler D. Puschmann R, et al. Among authors: fiedler d. Methods Enzymol. 2020;641:35-52. doi: 10.1016/bs.mie.2020.04.035. Epub 2020 Jun 12. Methods Enzymol. 2020. PMID: 32713530

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