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Natural mutation in the regulatory gene (srrG) influences virulence-associated genes and enhances invasiveness in Streptococcus dysgalactiae subsp. equisimilis strains isolated from cases of streptococcal toxic shock syndrome.
Ikebe T, Otsuka H, Chiba K, Kazawa Y, Yamaguchi T, Okuno R, Date Y, Sasaki M, Isobe J, Ohnishi M, Akeda Y. Ikebe T, et al. Among authors: date y. EBioMedicine. 2022 Jul;81:104133. doi: 10.1016/j.ebiom.2022.104133. Epub 2022 Jun 29. EBioMedicine. 2022. PMID: 35779495 Free PMC article.
Serotype Distribution and Antimicrobial Resistance of Streptococcus agalactiae Isolates in Nonpregnant Adults with Streptococcal Toxic Shock Syndrome in Japan in 2014 to 2021.
Ikebe T, Okuno R, Uchitani Y, Takano M, Yamaguchi T, Otsuka H, Kazawa Y, Fujita S, Kobayashi A, Date Y, Isobe J, Maenishi E, Ohnishi M, Akeda Y; Working Group for Beta-Hemolytic Streptococci in Japan. Ikebe T, et al. Among authors: date y. Microbiol Spectr. 2023 Feb 14;11(2):e0498722. doi: 10.1128/spectrum.04987-22. Online ahead of print. Microbiol Spectr. 2023. PMID: 36786620 Free PMC article.
Epidemiological shifts in and impact of COVID-19 on streptococcal toxic shock syndrome in Japan: A genotypic analysis of group A Streptococcus isolates.
Ikebe T, Okuno R, Uchitani Y, Yamaguchi T, Isobe J, Maenishi E, Date Y, Otsuka H, Kazawa Y, Fujita S, Kobayashi A, Takano M, Tsukamoto S, Kanda Y, Ohnishi M, Akeda Y; Working Group for Beta-Hemolytic Streptococci in Japan. Ikebe T, et al. Among authors: date y. Int J Infect Dis. 2024 May;142:106954. doi: 10.1016/j.ijid.2024.01.021. Epub 2024 Feb 19. Int J Infect Dis. 2024. PMID: 38382822 Free article.
Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery.
Morimoto S, Takahashi S, Ito D, Daté Y, Okada K, Kato C, Nakamura S, Ozawa F, Chyi CM, Nishiyama A, Suzuki N, Fujimori K, Kondo T, Takao M, Hirai M, Kabe Y, Suematsu M, Jinzaki M, Aoki M, Fujiki Y, Sato Y, Suzuki N, Nakahara J; Pooled Resource Open-Access ALS Clinical Trials Consortium; Okano H. Morimoto S, et al. Among authors: date y. Cell Stem Cell. 2023 Jun 1;30(6):766-780.e9. doi: 10.1016/j.stem.2023.04.017. Cell Stem Cell. 2023. PMID: 37267913 Free article. Clinical Trial.
p53 Deficiency-Dependent Oncogenicity of Runx3.
Ito K, Otani S, Date Y. Ito K, et al. Among authors: date y. Cells. 2023 Apr 10;12(8):1122. doi: 10.3390/cells12081122. Cells. 2023. PMID: 37190031 Free PMC article. Review.
288 results