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A water-soluble manganese(II) octanediaoate/phenanthroline complex acts as an antioxidant and attenuates alpha-synuclein toxicity.
Queiroz DD, Ribeiro TP, Gonçalves JM, Mattos LMM, Gerhardt E, Freitas J, Palhano FL, Frases S, Pinheiro AS, McCann M, Knox A, Devereux M, Outeiro TF, Pereira MD. Queiroz DD, et al. Among authors: palhano fl. Biochim Biophys Acta Mol Basis Dis. 2022 Oct 1;1868(10):166475. doi: 10.1016/j.bbadis.2022.166475. Epub 2022 Jun 28. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35777688 Free article.
The Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role against α-Synuclein Oligomers.
Latge C, Cabral KM, de Oliveira GA, Raymundo DP, Freitas JA, Johanson L, Romão LF, Palhano FL, Herrmann T, Almeida MS, Foguel D. Latge C, et al. Among authors: palhano fl. J Biol Chem. 2015 Aug 14;290(33):20527-40. doi: 10.1074/jbc.M115.662254. Epub 2015 Jul 6. J Biol Chem. 2015. PMID: 26149686 Free PMC article.
Cerebral dopamine neurotrophic factor reduces α-synuclein aggregation and propagation and alleviates behavioral alterations in vivo.
Albert K, Raymundo DP, Panhelainen A, Eesmaa A, Shvachiy L, Araújo GR, Chmielarz P, Yan X, Singh A, Cordeiro Y, Palhano FL, Foguel D, Luk KC, Domanskyi A, Voutilainen MH, Huttunen HJ, Outeiro TF, Saarma M, Almeida MS, Airavaara M. Albert K, et al. Among authors: palhano fl. Mol Ther. 2021 Sep 1;29(9):2821-2840. doi: 10.1016/j.ymthe.2021.04.035. Epub 2021 May 1. Mol Ther. 2021. PMID: 33940158 Free PMC article.
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species.
Santos CC, Cardim-Pires TR, Shvachiy L, Fonseca-Fonseca LA, Muñoz P, Almeida ÁMAN, Costa ACS, Teles-Souza J, Ochoa-Rodríguez E, de Fátima Dias Costa M, Palhano FL, Segura-Aguilar J, Barbosa DB, do Bomfim MR, Dos Santos Junior MC, Leite FHA, da Rocha Pita SS, Costa SL, Núñez-Figueredo Y, Outeiro TF, Foguel D, Silva VDA. Santos CC, et al. Among authors: palhano fl. Neurotox Res. 2022 Dec;40(6):2135-2147. doi: 10.1007/s12640-022-00559-7. Epub 2022 Aug 23. Neurotox Res. 2022. PMID: 35997936
A Metabolic Shift toward Pentose Phosphate Pathway Is Necessary for Amyloid Fibril- and Phorbol 12-Myristate 13-Acetate-induced Neutrophil Extracellular Trap (NET) Formation.
Azevedo EP, Rochael NC, Guimarães-Costa AB, de Souza-Vieira TS, Ganilho J, Saraiva EM, Palhano FL, Foguel D. Azevedo EP, et al. Among authors: palhano fl. J Biol Chem. 2015 Sep 4;290(36):22174-83. doi: 10.1074/jbc.M115.640094. Epub 2015 Jul 21. J Biol Chem. 2015. PMID: 26198639 Free PMC article.
45 results