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CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L. Lagarrigue S, et al. Among authors: tinahones fj. J Clin Invest. 2022 Jul 1;132(13):e162359. doi: 10.1172/JCI162359. J Clin Invest. 2022. PMID: 35775487 Free PMC article. No abstract available.
CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L. Lagarrigue S, et al. Among authors: tinahones fj. J Clin Invest. 2016 Jan;126(1):335-48. doi: 10.1172/JCI81480. Epub 2015 Dec 14. J Clin Invest. 2016. PMID: 26657864 Free PMC article.
The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes.
Lacroix M, Linares LK, Rueda-Rincon N, Bloch K, Di Michele M, De Blasio C, Fau C, Gayte L, Blanchet E, Mairal A, Derua R, Cardona F, Beuzelin D, Annicotte JS, Pirot N, Torro A, Tinahones FJ, Bernex F, Bertrand-Michel J, Langin D, Fajas L, Swinnen JV, Le Cam L. Lacroix M, et al. Among authors: tinahones fj. Nat Commun. 2021 Dec 2;12(1):7037. doi: 10.1038/s41467-021-27307-3. Nat Commun. 2021. PMID: 34857760 Free PMC article.
Zinc-alpha 2-glycoprotein gene expression in adipose tissue is related with insulin resistance and lipolytic genes in morbidly obese patients.
Garrido-Sánchez L, García-Fuentes E, Fernández-García D, Escoté X, Alcaide J, Perez-Martinez P, Vendrell J, Tinahones FJ. Garrido-Sánchez L, et al. Among authors: tinahones fj. PLoS One. 2012;7(3):e33264. doi: 10.1371/journal.pone.0033264. Epub 2012 Mar 19. PLoS One. 2012. PMID: 22442679 Free PMC article. Clinical Trial.
Study of the potential association of adipose tissue GLP-1 receptor with obesity and insulin resistance.
Vendrell J, El Bekay R, Peral B, García-Fuentes E, Megia A, Macias-Gonzalez M, Fernández Real J, Jimenez-Gomez Y, Escoté X, Pachón G, Simó R, Selva DM, Malagón MM, Tinahones FJ. Vendrell J, et al. Among authors: tinahones fj. Endocrinology. 2011 Nov;152(11):4072-9. doi: 10.1210/en.2011-1070. Epub 2011 Aug 23. Endocrinology. 2011. PMID: 21862620 Free article.
Munc18c in adipose tissue is downregulated in obesity and is associated with insulin.
Garrido-Sanchez L, Escote X, Coin-Aragüez L, Fernandez-Garcia JC, El Bekay R, Vendrell J, Garcia-Fuentes E, Tinahones FJ. Garrido-Sanchez L, et al. Among authors: tinahones fj. PLoS One. 2013 May 20;8(5):e63937. doi: 10.1371/journal.pone.0063937. Print 2013. PLoS One. 2013. PMID: 23700440 Free PMC article.
Zinc-α2-Glycoprotein Modulates AKT-Dependent Insulin Signaling in Human Adipocytes by Activation of the PP2A Phosphatase.
Ceperuelo-Mallafré V, Ejarque M, Duran X, Pachón G, Vázquez-Carballo A, Roche K, Núñez-Roa C, Garrido-Sánchez L, Tinahones FJ, Vendrell J, Fernández-Veledo S. Ceperuelo-Mallafré V, et al. Among authors: tinahones fj. PLoS One. 2015 Jun 11;10(6):e0129644. doi: 10.1371/journal.pone.0129644. eCollection 2015. PLoS One. 2015. PMID: 26068931 Free PMC article.
FABP4 dynamics in obesity: discrepancies in adipose tissue and liver expression regarding circulating plasma levels.
Queipo-Ortuño MI, Escoté X, Ceperuelo-Mallafré V, Garrido-Sanchez L, Miranda M, Clemente-Postigo M, Pérez-Pérez R, Peral B, Cardona F, Fernández-Real JM, Tinahones FJ, Vendrell J. Queipo-Ortuño MI, et al. Among authors: tinahones fj. PLoS One. 2012;7(11):e48605. doi: 10.1371/journal.pone.0048605. Epub 2012 Nov 5. PLoS One. 2012. PMID: 23139800 Free PMC article.
544 results