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CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L. Lagarrigue S, et al. Among authors: chavey c. J Clin Invest. 2022 Jul 1;132(13):e162359. doi: 10.1172/JCI162359. J Clin Invest. 2022. PMID: 35775487 Free PMC article. No abstract available.
CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L. Lagarrigue S, et al. Among authors: chavey c. J Clin Invest. 2016 Jan;126(1):335-48. doi: 10.1172/JCI81480. Epub 2015 Dec 14. J Clin Invest. 2016. PMID: 26657864 Free PMC article.
CDK4 Phosphorylates AMPKα2 to Inhibit Its Activity and Repress Fatty Acid Oxidation.
Lopez-Mejia IC, Lagarrigue S, Giralt A, Martinez-Carreres L, Zanou N, Denechaud PD, Castillo-Armengol J, Chavey C, Orpinell M, Delacuisine B, Nasrallah A, Collodet C, Zhang L, Viollet B, Hardie DG, Fajas L. Lopez-Mejia IC, et al. Among authors: chavey c. Mol Cell. 2017 Oct 19;68(2):336-349.e6. doi: 10.1016/j.molcel.2017.09.034. Mol Cell. 2017. PMID: 29053957 Free article.
The CDK4-pRB-E2F1 pathway controls insulin secretion.
Annicotte JS, Blanchet E, Chavey C, Iankova I, Costes S, Assou S, Teyssier J, Dalle S, Sardet C, Fajas L. Annicotte JS, et al. Among authors: chavey c. Nat Cell Biol. 2009 Aug;11(8):1017-23. doi: 10.1038/ncb1915. Epub 2009 Jul 13. Nat Cell Biol. 2009. PMID: 19597485 Free PMC article.
CXCL5 drives obesity to diabetes, and further.
Chavey C, Fajas L. Chavey C, et al. Aging (Albany NY). 2009 Jul 2;1(7):674-7. doi: 10.18632/aging.100064. Aging (Albany NY). 2009. PMID: 20157549 Free PMC article.
Antagonistic functions of LMNA isoforms in energy expenditure and lifespan.
Lopez-Mejia IC, de Toledo M, Chavey C, Lapasset L, Cavelier P, Lopez-Herrera C, Chebli K, Fort P, Beranger G, Fajas L, Amri EZ, Casas F, Tazi J. Lopez-Mejia IC, et al. Among authors: chavey c. EMBO Rep. 2014 May;15(5):529-39. doi: 10.1002/embr.201338126. Epub 2014 Mar 17. EMBO Rep. 2014. PMID: 24639560 Free PMC article.
Regulator of G protein signaling-4 controls fatty acid and glucose homeostasis.
Iankova I, Chavey C, Clapé C, Colomer C, Guérineau NC, Grillet N, Brunet JF, Annicotte JS, Fajas L. Iankova I, et al. Among authors: chavey c. Endocrinology. 2008 Nov;149(11):5706-12. doi: 10.1210/en.2008-0717. Epub 2008 Jul 17. Endocrinology. 2008. PMID: 18635652 Free PMC article.
E2F transcription factor-1 regulates oxidative metabolism.
Blanchet E, Annicotte JS, Lagarrigue S, Aguilar V, Clapé C, Chavey C, Fritz V, Casas F, Apparailly F, Auwerx J, Fajas L. Blanchet E, et al. Among authors: chavey c. Nat Cell Biol. 2011 Aug 14;13(9):1146-52. doi: 10.1038/ncb2309. Nat Cell Biol. 2011. PMID: 21841792 Free PMC article.
KAT2B Is Required for Pancreatic Beta Cell Adaptation to Metabolic Stress by Controlling the Unfolded Protein Response.
Rabhi N, Denechaud PD, Gromada X, Hannou SA, Zhang H, Rashid T, Salas E, Durand E, Sand O, Bonnefond A, Yengo L, Chavey C, Bonner C, Kerr-Conte J, Abderrahmani A, Auwerx J, Fajas L, Froguel P, Annicotte JS. Rabhi N, et al. Among authors: chavey c. Cell Rep. 2016 May 3;15(5):1051-1061. doi: 10.1016/j.celrep.2016.03.079. Epub 2016 Apr 21. Cell Rep. 2016. PMID: 27117420 Free article.
32 results