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CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L. Lagarrigue S, et al. Among authors: abella a. J Clin Invest. 2022 Jul 1;132(13):e162359. doi: 10.1172/JCI162359. J Clin Invest. 2022. PMID: 35775487 Free PMC article. No abstract available.
CDK4 is an essential insulin effector in adipocytes.
Lagarrigue S, Lopez-Mejia IC, Denechaud PD, Escoté X, Castillo-Armengol J, Jimenez V, Chavey C, Giralt A, Lai Q, Zhang L, Martinez-Carreres L, Delacuisine B, Annicotte JS, Blanchet E, Huré S, Abella A, Tinahones FJ, Vendrell J, Dubus P, Bosch F, Kahn CR, Fajas L. Lagarrigue S, et al. Among authors: abella a. J Clin Invest. 2016 Jan;126(1):335-48. doi: 10.1172/JCI81480. Epub 2015 Dec 14. J Clin Invest. 2016. PMID: 26657864 Free PMC article.
Cdk4 promotes adipogenesis through PPARgamma activation.
Abella A, Dubus P, Malumbres M, Rane SG, Kiyokawa H, Sicard A, Vignon F, Langin D, Barbacid M, Fajas L. Abella A, et al. Cell Metab. 2005 Oct;2(4):239-49. doi: 10.1016/j.cmet.2005.09.003. Cell Metab. 2005. PMID: 16213226 Free article.
Oral insulin-mimetic compounds that act independently of insulin.
García-Vicente S, Yraola F, Marti L, González-Muñoz E, García-Barrado MJ, Cantó C, Abella A, Bour S, Artuch R, Sierra C, Brandi N, Carpéné C, Moratinos J, Camps M, Palacín M, Testar X, Gumà A, Albericio F, Royo M, Mian A, Zorzano A. García-Vicente S, et al. Among authors: abella a. Diabetes. 2007 Feb;56(2):486-93. doi: 10.2337/db06-0269. Diabetes. 2007. PMID: 17259395
Substrates of semicarbazide-sensitive amine oxidase co-operate with vanadate to stimulate tyrosine phosphorylation of insulin-receptor-substrate proteins, phosphoinositide 3-kinase activity and GLUT4 translocation in adipose cells.
Enrique-Tarancón G, Castan I, Morin N, Marti L, Abella A, Camps M, Casamitjana R, Palacín M, Testar X, Degerman E, Carpéné C, Zorzano A. Enrique-Tarancón G, et al. Among authors: abella a. Biochem J. 2000 Aug 15;350 Pt 1(Pt 1):171-80. Biochem J. 2000. PMID: 10926841 Free PMC article.
105 results