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BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors.
Sevdali E, Block V, Lataretu M, Li H, Smulski CR, Briem JS, Heitz Y, Fischer B, Ramirez NJ, Grimbacher B, Jäck HM, Voll RE, Hölzer M, Schneider P, Eibel H. Sevdali E, et al. Among authors: smulski cr. Cell Rep. 2022 Jun 28;39(13):111019. doi: 10.1016/j.celrep.2022.111019. Cell Rep. 2022. PMID: 35767961 Free article.
A common single nucleotide polymorphism impairs B-cell activating factor receptor's multimerization, contributing to common variable immunodeficiency.
Pieper K, Rizzi M, Speletas M, Smulski CR, Sic H, Kraus H, Salzer U, Fiala GJ, Schamel WW, Lougaris V, Plebani A, Hammarstrom L, Recher M, Germenis AE, Grimbacher B, Warnatz K, Rolink AG, Schneider P, Notarangelo LD, Eibel H. Pieper K, et al. Among authors: smulski cr. J Allergy Clin Immunol. 2014 Apr;133(4):1222-5. doi: 10.1016/j.jaci.2013.11.021. Epub 2014 Jan 7. J Allergy Clin Immunol. 2014. PMID: 24406071 No abstract available.
Stoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties.
Schuepbach-Mallepell S, Das D, Willen L, Vigolo M, Tardivel A, Lebon L, Kowalczyk-Quintas C, Nys J, Smulski C, Zheng TS, Maskos K, Lammens A, Jiang X, Hess H, Tan SL, Schneider P. Schuepbach-Mallepell S, et al. J Biol Chem. 2015 Jun 26;290(26):16330-42. doi: 10.1074/jbc.M115.661405. Epub 2015 May 7. J Biol Chem. 2015. PMID: 25953898 Free PMC article.
Antibodies That Block or Activate Mouse B Cell Activating Factor of the Tumor Necrosis Factor (TNF) Family (BAFF), Respectively, Induce B Cell Depletion or B Cell Hyperplasia.
Kowalczyk-Quintas C, Schuepbach-Mallepell S, Vigolo M, Willen L, Tardivel A, Smulski CR, Zheng TS, Gommerman J, Hess H, Gottenberg JE, Mackay F, Donzé O, Schneider P. Kowalczyk-Quintas C, et al. Among authors: smulski cr. J Biol Chem. 2016 Sep 16;291(38):19826-34. doi: 10.1074/jbc.M116.725929. Epub 2016 Jul 22. J Biol Chem. 2016. PMID: 27451394 Free PMC article.
A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors.
Vigolo M, Chambers MG, Willen L, Chevalley D, Maskos K, Lammens A, Tardivel A, Das D, Kowalczyk-Quintas C, Schuepbach-Mallepell S, Smulski CR, Eslami M, Rolink A, Hummler E, Samy E, Fomekong Nanfack Y, Mackay F, Liao M, Hess H, Jiang X, Schneider P. Vigolo M, et al. Among authors: smulski cr. Nat Commun. 2018 Mar 23;9(1):1199. doi: 10.1038/s41467-018-03323-8. Nat Commun. 2018. PMID: 29572442 Free PMC article.
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