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Terbinafine prevents colorectal cancer growth by inducing dNTP starvation and reducing immune suppression.
Hu LP, Huang W, Wang X, Xu C, Qin WT, Li D, Tian G, Li Q, Zhou Y, Chen S, Nie HZ, Hao Y, Song J, Zhang XL, Sundquist J, Sundquist K, Li J, Jiang SH, Zhang ZG, Ji J. Hu LP, et al. Among authors: li d, li j, li q. Mol Ther. 2022 Oct 5;30(10):3284-3299. doi: 10.1016/j.ymthe.2022.06.015. Epub 2022 Jun 27. Mol Ther. 2022. PMID: 35765243 Free PMC article.
Nucleolar HEAT Repeat Containing 1 Up-regulated by the Mechanistic Target of Rapamycin Complex 1 Signaling Promotes Hepatocellular Carcinoma Growth by Dominating Ribosome Biogenesis and Proteome Homeostasis.
Yang XM, Wang XQ, Hu LP, Feng MX, Zhou YQ, Li DX, Li J, Miao XC, Zhang YL, Yao LL, Nie HZ, Huang S, Xia Q, Zhang XL, Jiang SH, Zhang ZG. Yang XM, et al. Gastroenterology. 2023 Sep;165(3):629-646. doi: 10.1053/j.gastro.2023.05.029. Epub 2023 May 27. Gastroenterology. 2023. PMID: 37247644
A GAPDH serotonylation system couples CD8+ T cell glycolytic metabolism to antitumor immunity.
Wang X, Fu SQ, Yuan X, Yu F, Ji Q, Tang HW, Li RK, Huang S, Huang PQ, Qin WT, Zuo H, Du C, Yao LL, Li H, Li J, Li DX, Yang Y, Xiao SY, Tulamaiti A, Wang XF, Dai CH, Zhang X, Jiang SH, Hu LP, Zhang XL, Zhang ZG. Wang X, et al. Mol Cell. 2024 Feb 15;84(4):760-775.e7. doi: 10.1016/j.molcel.2023.12.015. Epub 2024 Jan 11. Mol Cell. 2024. PMID: 38215751
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