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Controlled masking and targeted release of redox-cycling ortho-quinones via a C-C bond-cleaving 1,6-elimination.
Dunsmore L, Navo CD, Becher J, de Montes EG, Guerreiro A, Hoyt E, Brown L, Zelenay V, Mikutis S, Cooper J, Barbieri I, Lawrinowitz S, Siouve E, Martin E, Ruivo PR, Rodrigues T, da Cruz FP, Werz O, Vassiliou G, Ravn P, Jiménez-Osés G, Bernardes GJL. Dunsmore L, et al. Among authors: rodrigues t. Nat Chem. 2022 Jul;14(7):754-765. doi: 10.1038/s41557-022-00964-7. Epub 2022 Jun 27. Nat Chem. 2022. PMID: 35764792 Free PMC article.
Revealing the macromolecular targets of complex natural products.
Reker D, Perna AM, Rodrigues T, Schneider P, Reutlinger M, Mönch B, Koeberle A, Lamers C, Gabler M, Steinmetz H, Müller R, Schubert-Zsilavecz M, Werz O, Schneider G. Reker D, et al. Among authors: rodrigues t. Nat Chem. 2014 Dec;6(12):1072-8. doi: 10.1038/nchem.2095. Epub 2014 Nov 2. Nat Chem. 2014. PMID: 25411885
Unveiling (-)-Englerin A as a Modulator of L-Type Calcium Channels.
Rodrigues T, Sieglitz F, Somovilla VJ, Cal PM, Galione A, Corzana F, Bernardes GJ. Rodrigues T, et al. Angew Chem Int Ed Engl. 2016 Sep 5;55(37):11077-81. doi: 10.1002/anie.201604336. Epub 2016 Jul 8. Angew Chem Int Ed Engl. 2016. PMID: 27391219 Free PMC article.
Antibody-drug conjugates: The missing link.
Rodrigues T, Bernardes GJ. Rodrigues T, et al. Nat Chem. 2016 Nov 22;8(12):1088-1090. doi: 10.1038/nchem.2685. Nat Chem. 2016. PMID: 27874863 No abstract available.
Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells.
Jiménez-Moreno E, Guo Z, Oliveira BL, Albuquerque IS, Kitowski A, Guerreiro A, Boutureira O, Rodrigues T, Jiménez-Osés G, Bernardes GJ. Jiménez-Moreno E, et al. Among authors: rodrigues t. Angew Chem Int Ed Engl. 2017 Jan 2;56(1):243-247. doi: 10.1002/anie.201609607. Epub 2016 Dec 8. Angew Chem Int Ed Engl. 2017. PMID: 27930843 Free PMC article.
1,093 results