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A novel synthetic peptide SVHRSP attenuates dopaminergic neurodegeneration by inhibiting NADPH oxidase-mediated neuroinflammation in experimental models of Parkinson's disease.
Zhang X, Tu D, Li S, Li N, Li D, Gao Y, Tian L, Liu J, Zhang X, Hong JS, Hou L, Zhao J, Wang Q. Zhang X, et al. Among authors: li s, li d, li n. Free Radic Biol Med. 2022 Aug 1;188:363-374. doi: 10.1016/j.freeradbiomed.2022.06.241. Epub 2022 Jun 24. Free Radic Biol Med. 2022. PMID: 35760232
Influence of nigrostriatal dopaminergic tone on the biosynthesis of dynorphin and enkephalin in rat striatum.
Li SJ, Jiang HK, Stachowiak MS, Hudson PM, Owyang V, Nanry K, Tilson HA, Hong JS. Li SJ, et al. Brain Res Mol Brain Res. 1990 Aug;8(3):219-25. doi: 10.1016/0169-328x(90)90020-e. Brain Res Mol Brain Res. 1990. PMID: 1977070
Activation of DA receptors by 7 daily injections of APO (5 mg/kg, Bid, s.c.), however, caused a large increase (3- to 4-fold of saline control) in striatal levels of DN-LI and prodynorphin mRNA on the 6-OHDA lesioned side, which is far greater than the increase on t …
Activation of DA receptors by 7 daily injections of APO (5 mg/kg, Bid, s.c.), however, caused a large increase (3- to 4-fold of salin …
Dopaminergic regulation of tachykinin metabolism in the striatonigral pathway.
Li SJ, Sivam SP, McGinty JF, Huang YS, Hong JS. Li SJ, et al. J Pharmacol Exp Ther. 1987 Nov;243(2):792-8. J Pharmacol Exp Ther. 1987. PMID: 2445959
Immunocytochemical staining revealed enhanced SP-LI in neurons restricted to striatal patches and fibers in substantia nigra pars reticulata after APO treatment as compared with SP-LI intensity in control. ...These results suggest that stimulation of dopaminergic re …
Immunocytochemical staining revealed enhanced SP-LI in neurons restricted to striatal patches and fibers in substantia nigra pars ret …
Regulation of the metabolism of striatal dynorphin by the dopaminergic system.
Li SJ, Sivam SP, McGinty JF, Jiang HK, Douglass J, Calavetta L, Hong JS. Li SJ, et al. J Pharmacol Exp Ther. 1988 Jul;246(1):403-8. J Pharmacol Exp Ther. 1988. PMID: 2899169
Seven daily injections of a dopamine (DA) agonist, apomorphine (APO, 5 mg/kg, b.i.d., s.c.), caused a significant increase of dynorphin A (1-8)-like immunoreactivity (DN-LI) in the striatum (140% over control) and substantia nigra (41% over control) without changing …
Seven daily injections of a dopamine (DA) agonist, apomorphine (APO, 5 mg/kg, b.i.d., s.c.), caused a significant increase of dynorph …
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