Salmena L - Search Results

1

Inhibition of lipid kinase PIKfyve reveals a role for phosphatase Inpp4b in the regulation of PI(3)P-mediated lysosome dynamics through VPS34 activity.

Saffi GT, Wang CA, Mangialardi EM, Vacher J, Botelho RJ, Salmena L. Saffi GT, et al. Among authors: salmena l. J Biol Chem. 2022 Aug;298(8):102187. doi: 10.1016/j.jbc.2022.102187. Epub 2022 Jun 26. J Biol Chem. 2022. PMID: 35760104 Free PMC article.

2

Phosphoinositide signaling in cancer: INPP4B Akt(s) out.

Woolley JF, Dzneladze I, Salmena L. Woolley JF, et al. Among authors: salmena l. Trends Mol Med. 2015 Sep;21(9):530-2. doi: 10.1016/j.molmed.2015.06.006. Epub 2015 Jul 3. Trends Mol Med. 2015. PMID: 26150301

3

Investigating the duality of Inpp4b function in the cellular transformation of mouse fibroblasts.

Mangialardi EM, Chen K, Salmon B, Vacher J, Salmena L. Mangialardi EM, et al. Among authors: salmena l. Oncotarget. 2019 Oct 29;10(59):6378-6390. doi: 10.18632/oncotarget.27293. eCollection 2019 Oct 29. Oncotarget. 2019. PMID: 31695845 Free PMC article.

4

Reactive oxygen species prevent lysosome coalescence during PIKfyve inhibition.

Saffi GT, Tang E, Mamand S, Inpanathan S, Fountain A, Salmena L, Botelho RJ. Saffi GT, et al. Among authors: salmena l. PLoS One. 2021 Nov 23;16(11):e0259313. doi: 10.1371/journal.pone.0259313. eCollection 2021. PLoS One. 2021. PMID: 34813622 Free PMC article.

5

Essential role for caspase-8 in Toll-like receptors and NFkappaB signaling.

Lemmers B, Salmena L, Bidère N, Su H, Matysiak-Zablocki E, Murakami K, Ohashi PS, Jurisicova A, Lenardo M, Hakem R, Hakem A. Lemmers B, et al. Among authors: salmena l. J Biol Chem. 2007 Mar 9;282(10):7416-23. doi: 10.1074/jbc.M606721200. Epub 2007 Jan 9. J Biol Chem. 2007. PMID: 17213198 Free article.

6

INPP4B overexpression is associated with poor clinical outcome and therapy resistance in acute myeloid leukemia.

Dzneladze I, He R, Woolley JF, Son MH, Sharobim MH, Greenberg SA, Gabra M, Langlois C, Rashid A, Hakem A, Ibrahimova N, Arruda A, Löwenberg B, Valk PJ, Minden MD, Salmena L. Dzneladze I, et al. Among authors: salmena l. Leukemia. 2015 Jul;29(7):1485-95. doi: 10.1038/leu.2015.51. Epub 2015 Mar 4. Leukemia. 2015. PMID: 25736236

7

SubID, a non-median dichotomization tool for heterogeneous populations, reveals the pan-cancer significance of INPP4B and its regulation by EVI1 in AML.

Dzneladze I, Woolley JF, Rossell C, Han Y, Rashid A, Jain M, Reimand J, Minden MD, Salmena L. Dzneladze I, et al. Among authors: salmena l. PLoS One. 2018 Feb 7;13(2):e0191510. doi: 10.1371/journal.pone.0191510. eCollection 2018. PLoS One. 2018. PMID: 29415082 Free PMC article.

8

In Vivo Role of INPP4B in Tumor and Metastasis Suppression through Regulation of PI3K-AKT Signaling at Endosomes.

Li Chew C, Lunardi A, Gulluni F, Ruan DT, Chen M, Salmena L, Nishino M, Papa A, Ng C, Fung J, Clohessy JG, Sasaki J, Sasaki T, Bronson RT, Hirsch E, Pandolfi PP. Li Chew C, et al. Among authors: salmena l. Cancer Discov. 2015 Jul;5(7):740-51. doi: 10.1158/2159-8290.CD-14-1347. Epub 2015 Apr 16. Cancer Discov. 2015. PMID: 25883022 Free PMC article.

9

Recent advances in PTEN signalling axes in cancer.

Chow JT, Salmena L. Chow JT, et al. Among authors: salmena l. Fac Rev. 2020 Dec 23;9:31. doi: 10.12703/r/9-31. eCollection 2020. Fac Rev. 2020. PMID: 33659963 Free PMC article. Review.

10

The Complex Landscape of PTEN mRNA Regulation.

Sellars E, Gabra M, Salmena L. Sellars E, et al. Among authors: salmena l. Cold Spring Harb Perspect Med. 2020 Jun 1;10(6):a036236. doi: 10.1101/cshperspect.a036236. Cold Spring Harb Perspect Med. 2020. PMID: 31871240 Free PMC article. Review.

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