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Desymmetrization of pibrentasvir for efficient prodrug synthesis.
Voight EA, Greszler SN, Hartung J, Ji J, Klix RC, Randolph JT, Shelat BH, Waters JE, DeGoey DA. Voight EA, et al. Chem Sci. 2021 Jun 29;12(29):10076-10082. doi: 10.1039/d1sc02396a. eCollection 2021 Jul 28. Chem Sci. 2021. PMID: 34349971 Free PMC article.
Fueling the Pipeline via Innovations in Organic Synthesis.
Voight EA, Greszler SN, Kym PR. Voight EA, et al. ACS Med Chem Lett. 2021 Aug 27;12(9):1365-1373. doi: 10.1021/acsmedchemlett.1c00351. eCollection 2021 Sep 9. ACS Med Chem Lett. 2021. PMID: 34531945 Free PMC article.
Synthesis and Pharmacology of (Pyridin-2-yl)methanol Derivatives as Novel and Selective Transient Receptor Potential Vanilloid 3 Antagonists.
Gomtsyan A, Schmidt RG, Bayburt EK, Gfesser GA, Voight EA, Daanen JF, Schmidt DL, Cowart MD, Liu H, Altenbach RJ, Kort ME, Clapham B, Cox PB, Shrestha A, Henry R, Whittern DN, Reilly RM, Puttfarcken PS, Brederson JD, Song P, Li B, Huang SM, McDonald HA, Neelands TR, McGaraughty SP, Gauvin DM, Joshi SK, Banfor PN, Segreti JA, Shebley M, Faltynek CR, Dart MJ, Kym PR. Gomtsyan A, et al. Among authors: voight ea. J Med Chem. 2016 May 26;59(10):4926-47. doi: 10.1021/acs.jmedchem.6b00287. Epub 2016 May 2. J Med Chem. 2016. PMID: 27077528
41 results