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Escape in one of two cytotoxic T-lymphocyte epitopes bound by a high-frequency major histocompatibility complex class I molecule, Mamu-A*02: a paradigm for virus evolution and persistence?
Vogel TU, Friedrich TC, O'Connor DH, Rehrauer W, Dodds EJ, Hickman H, Hildebrand W, Sidney J, Sette A, Hughes A, Horton H, Vielhuber K, Rudersdorf R, De Souza IP, Reynolds MR, Allen TM, Wilson N, Watkins DI. Vogel TU, et al. Among authors: friedrich tc. J Virol. 2002 Nov;76(22):11623-36. doi: 10.1128/jvi.76.22.11623-11636.2002. J Virol. 2002. PMID: 12388723 Free PMC article.
Extraepitopic compensatory substitutions partially restore fitness to simian immunodeficiency virus variants that escape from an immunodominant cytotoxic-T-lymphocyte response.
Friedrich TC, Frye CA, Yant LJ, O'Connor DH, Kriewaldt NA, Benson M, Vojnov L, Dodds EJ, Cullen C, Rudersdorf R, Hughes AL, Wilson N, Watkins DI. Friedrich TC, et al. J Virol. 2004 Mar;78(5):2581-5. doi: 10.1128/jvi.78.5.2581-2585.2004. J Virol. 2004. PMID: 14963161 Free PMC article.
Reversion of CTL escape-variant immunodeficiency viruses in vivo.
Friedrich TC, Dodds EJ, Yant LJ, Vojnov L, Rudersdorf R, Cullen C, Evans DT, Desrosiers RC, Mothé BR, Sidney J, Sette A, Kunstman K, Wolinsky S, Piatak M, Lifson J, Hughes AL, Wilson N, O'Connor DH, Watkins DI. Friedrich TC, et al. Nat Med. 2004 Mar;10(3):275-81. doi: 10.1038/nm998. Epub 2004 Feb 15. Nat Med. 2004. PMID: 14966520
Vaccine-induced cellular immune responses reduce plasma viral concentrations after repeated low-dose challenge with pathogenic simian immunodeficiency virus SIVmac239.
Wilson NA, Reed J, Napoe GS, Piaskowski S, Szymanski A, Furlott J, Gonzalez EJ, Yant LJ, Maness NJ, May GE, Soma T, Reynolds MR, Rakasz E, Rudersdorf R, McDermott AB, O'Connor DH, Friedrich TC, Allison DB, Patki A, Picker LJ, Burton DR, Lin J, Huang L, Patel D, Heindecker G, Fan J, Citron M, Horton M, Wang F, Liang X, Shiver JW, Casimiro DR, Watkins DI. Wilson NA, et al. Among authors: friedrich tc. J Virol. 2006 Jun;80(12):5875-85. doi: 10.1128/JVI.00171-06. J Virol. 2006. PMID: 16731926 Free PMC article.
Infection with "escaped" virus variants impairs control of simian immunodeficiency virus SIVmac239 replication in Mamu-B*08-positive macaques.
Valentine LE, Loffredo JT, Bean AT, León EJ, MacNair CE, Beal DR, Piaskowski SM, Klimentidis YC, Lank SM, Wiseman RW, Weinfurter JT, May GE, Rakasz EG, Wilson NA, Friedrich TC, O'Connor DH, Allison DB, Watkins DI. Valentine LE, et al. Among authors: friedrich tc. J Virol. 2009 Nov;83(22):11514-27. doi: 10.1128/JVI.01298-09. Epub 2009 Sep 2. J Virol. 2009. PMID: 19726517 Free PMC article.
Extralymphoid CD8+ T cells resident in tissue from simian immunodeficiency virus SIVmac239{Delta}nef-vaccinated macaques suppress SIVmac239 replication ex vivo.
Greene JM, Lhost JJ, Burwitz BJ, Budde ML, Macnair CE, Weiker MK, Gostick E, Friedrich TC, Broman KW, Price DA, O'Connor SL, O'Connor DH. Greene JM, et al. Among authors: friedrich tc. J Virol. 2010 Apr;84(7):3362-72. doi: 10.1128/JVI.02028-09. Epub 2010 Jan 20. J Virol. 2010. PMID: 20089651 Free PMC article.
MHC heterozygote advantage in simian immunodeficiency virus-infected Mauritian cynomolgus macaques.
O'Connor SL, Lhost JJ, Becker EA, Detmer AM, Johnson RC, Macnair CE, Wiseman RW, Karl JA, Greene JM, Burwitz BJ, Bimber BN, Lank SM, Tuscher JJ, Mee ET, Rose NJ, Desrosiers RC, Hughes AL, Friedrich TC, Carrington M, O'Connor DH. O'Connor SL, et al. Among authors: friedrich tc. Sci Transl Med. 2010 Mar 10;2(22):22ra18. doi: 10.1126/scitranslmed.3000524. Sci Transl Med. 2010. PMID: 20375000 Free PMC article.
187 results