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Design, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia.
Bertrand J, Dostálová H, Kryštof V, Jorda R, Delgado T, Castro-Alvarez A, Mella J, Cabezas D, Faúndez M, Espinosa-Bustos C, Salas CO. Bertrand J, et al. Among authors: delgado t. Pharmaceutics. 2022 Jun 17;14(6):1294. doi: 10.3390/pharmaceutics14061294. Pharmaceutics. 2022. PMID: 35745866 Free PMC article.
New Inhibitors of Bcr-Abl Based on 2,6,9-Trisubstituted Purine Scaffold Elicit Cytotoxicity in Chronic Myeloid Leukemia-Derived Cell Lines Sensitive and Resistant to TKIs.
Delgado T, Veselá D, Dostálová H, Kryštof V, Vojáčková V, Jorda R, Castro A, Bertrand J, Rivera G, Faúndez M, Strnad M, Espinosa-Bustos C, Salas CO. Delgado T, et al. Pharmaceutics. 2024 May 11;16(5):649. doi: 10.3390/pharmaceutics16050649. Pharmaceutics. 2024. PMID: 38794311 Free PMC article.
aProceedings of the 5th Meeting of Translational Hepatology, organized by the Spanish Association for the Study of the Liver (AEEH).
Tapias EA, Miles DM, Albillos A, Aller R, Ampuero J, Andrade R, Arechederra M, Aspichueta P, Banales JM, García AB, Caparros E, Delgado TC, Vico AC, Claria J, Cubero FJ, Ruiz AD, Fernández-Barrena MG, Iglesias AF, Veledo SF, Francés R, Durán RG, Sancho JG, Irimia M, Lens S, Martínez-Chantar ML, Mínguez B, Hernández RM, Nogueiras R, Molina BR, Barciela MR, Rodríguez-Perálvarez ML, Gómez MR, Sabio G, Bru PS, Cots MV, Vidal S, Gahete MD. Tapias EA, et al. Among authors: delgado tc. Gastroenterol Hepatol. 2024 May 7:502207. doi: 10.1016/j.gastrohep.2024.502207. Online ahead of print. Gastroenterol Hepatol. 2024. PMID: 38723772 Free article. English, Spanish.
Metallothionein-3 is a multifunctional driver that modulates the development of sorafenib-resistant phenotype in hepatocellular carcinoma cells.
Rodrigo MAM, Michalkova H, Jimenez AMJ, Petrlak F, Do T, Sivak L, Haddad Y, Kubickova P, de Los Rios V, Casal JI, Serrano-Macia M, Delgado TC, Boix L, Bruix J, Martinez Chantar ML, Adam V, Heger Z. Rodrigo MAM, et al. Among authors: delgado tc. Biomark Res. 2024 Apr 9;12(1):38. doi: 10.1186/s40364-024-00584-y. Biomark Res. 2024. PMID: 38594765 Free PMC article.
Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1.
Rodríguez-Agudo R, González-Recio I, Serrano-Maciá M, Bravo M, Petrov P, Blaya D, Herranz JM, Mercado-Gómez M, Rejano-Gordillo CM, Lachiondo-Ortega S, Gil-Pitarch C, Azkargorta M, Van Liempd SM, Martinez-Cruz LA, Simão AL, Elortza F, Martín C, Nevzorova YA, Cubero FJ, Delgado TC, Argemi J, Bataller R, Schoonjans K, Banales JM, Castro RE, Sancho-Bru P, Avila MA, Julve J, Jover R, Mabe J, Simon J, Goikoetxea-Usandizaga N, Martínez-Chantar ML. Rodríguez-Agudo R, et al. Among authors: delgado tc. JHEP Rep. 2023 Sep 30;6(1):100918. doi: 10.1016/j.jhepr.2023.100918. eCollection 2024 Jan. JHEP Rep. 2023. PMID: 38192540 Free PMC article.
222 results