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Discovery of Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L.
Meewan I, Kattoula J, Kattoula JY, Skinner D, Fajtová P, Giardini MA, Woodworth B, McKerrow JH, Lage de Siqueira-Neto J, O'Donoghue AJ, Abagyan R. Meewan I, et al. Among authors: abagyan r. Pharmaceuticals (Basel). 2022 Jun 13;15(6):744. doi: 10.3390/ph15060744. Pharmaceuticals (Basel). 2022. PMID: 35745663 Free PMC article.
Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.
Long T, Rojo-Arreola L, Shi D, El-Sakkary N, Jarnagin K, Rock F, Meewan M, Rascón AA Jr, Lin L, Cunningham KA, Lemieux GA, Podust L, Abagyan R, Ashrafi K, McKerrow JH, Caffrey CR. Long T, et al. Among authors: abagyan r. PLoS Negl Trop Dis. 2017 Jul 13;11(7):e0005680. doi: 10.1371/journal.pntd.0005680. eCollection 2017 Jul. PLoS Negl Trop Dis. 2017. PMID: 28704396 Free PMC article.
Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols.
Lebouvier N, Pagniez F, Na YM, Shi D, Pinson P, Marchivie M, Guillon J, Hakki T, Bernhardt R, Yee SW, Simons C, Lézé MP, Hartmann RW, Mularoni A, Le Baut G, Krimm I, Abagyan R, Le Pape P, Le Borgne M. Lebouvier N, et al. Among authors: abagyan r. Pharmaceuticals (Basel). 2020 Aug 8;13(8):186. doi: 10.3390/ph13080186. Pharmaceuticals (Basel). 2020. PMID: 32784450 Free PMC article.
Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors.
Kufareva I, Bestgen B, Brear P, Prudent R, Laudet B, Moucadel V, Ettaoussi M, Sautel CF, Krimm I, Engel M, Filhol O, Borgne ML, Lomberget T, Cochet C, Abagyan R. Kufareva I, et al. Among authors: abagyan r. Sci Rep. 2019 Nov 4;9(1):15893. doi: 10.1038/s41598-019-52141-5. Sci Rep. 2019. PMID: 31685885 Free PMC article.
343 results