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Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation.
Pajed L, Wagner C, Taschler U, Schreiber R, Kolleritsch S, Fawzy N, Pototschnig I, Schoiswohl G, Pusch LM, Wieser BI, Vesely P, Hoefler G, Eichmann TO, Zimmermann R, Lass A. Pajed L, et al. Among authors: wagner c. J Biol Chem. 2019 Jun 7;294(23):9118-9133. doi: 10.1074/jbc.RA118.007201. Epub 2019 Apr 25. J Biol Chem. 2019. PMID: 31023823 Free PMC article.
Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation.
Wagner C, Hois V, Pajed L, Pusch LM, Wolinski H, Trauner M, Zimmermann R, Taschler U, Lass A. Wagner C, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Aug;1865(8):158730. doi: 10.1016/j.bbalip.2020.158730. Epub 2020 May 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2020. PMID: 32361002 Free PMC article.
Advanced lipodystrophy reverses fatty liver in mice lacking adipocyte hormone-sensitive lipase.
Pajed L, Taschler U, Tilp A, Hofer P, Kotzbeck P, Kolleritsch S, Radner FPW, Pototschnig I, Wagner C, Schratter M, Eder S, Huetter S, Schreiber R, Haemmerle G, Eichmann TO, Schweiger M, Hoefler G, Kershaw EE, Lass A, Schoiswohl G. Pajed L, et al. Among authors: wagner c. Commun Biol. 2021 Mar 10;4(1):323. doi: 10.1038/s42003-021-01858-z. Commun Biol. 2021. PMID: 33692445 Free PMC article.
ATGL-dependent white adipose tissue lipolysis controls hepatocyte PPARα activity.
Fougerat A, Schoiswohl G, Polizzi A, Régnier M, Wagner C, Smati S, Fougeray T, Lippi Y, Lasserre F, Raho I, Melin V, Tramunt B, Métivier R, Sommer C, Benhamed F, Alkhoury C, Greulich F, Jouffe C, Emile A, Schupp M, Gourdy P, Dubot P, Levade T, Meynard D, Ellero-Simatos S, Gamet-Payrastre L, Panasyuk G, Uhlenhaut H, Amri EZ, Cruciani-Guglielmacci C, Postic C, Wahli W, Loiseau N, Montagner A, Langin D, Lass A, Guillou H. Fougerat A, et al. Among authors: wagner c. Cell Rep. 2022 Jun 7;39(10):110910. doi: 10.1016/j.celrep.2022.110910. Cell Rep. 2022. PMID: 35675775 Free article.
Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression.
Steinhoff JS, Wagner C, Taschler U, Wulff S, Kiefer MF, Petricek KM, Wowro SJ, Oster M, Flores RE, Yang N, Li C, Meng Y, Sommerfeld M, Weger S, Henze A, Raila J, Lass A, Schupp M. Steinhoff JS, et al. Among authors: wagner c. J Lipid Res. 2022 Oct;63(10):100268. doi: 10.1016/j.jlr.2022.100268. Epub 2022 Aug 27. J Lipid Res. 2022. PMID: 36030930 Free PMC article.
Adipocyte HSL is required for maintaining circulating vitamin A and RBP4 levels during fasting.
Steinhoff JS, Wagner C, Dähnhardt HE, Košić K, Meng Y, Taschler U, Pajed L, Yang N, Wulff S, Kiefer MF, Petricek KM, Flores RE, Li C, Dittrich S, Sommerfeld M, Guillou H, Henze A, Raila J, Wowro SJ, Schoiswohl G, Lass A, Schupp M. Steinhoff JS, et al. Among authors: wagner c. EMBO Rep. 2024 May 20. doi: 10.1038/s44319-024-00158-x. Online ahead of print. EMBO Rep. 2024. PMID: 38769419 Free article.
3,153 results