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Evolving cryo-EM structural approaches for GPCR drug discovery.
Zhang X, Johnson RM, Drulyte I, Yu L, Kotecha A, Danev R, Wootten D, Sexton PM, Belousoff MJ. Zhang X, et al. Among authors: johnson rm. Structure. 2021 Sep 2;29(9):963-974.e6. doi: 10.1016/j.str.2021.04.008. Epub 2021 May 5. Structure. 2021. PMID: 33957078 Free article.
A structural basis for amylin receptor phenotype.
Cao J, Belousoff MJ, Liang YL, Johnson RM, Josephs TM, Fletcher MM, Christopoulos A, Hay DL, Danev R, Wootten D, Sexton PM. Cao J, et al. Among authors: johnson rm. Science. 2022 Mar 25;375(6587):eabm9609. doi: 10.1126/science.abm9609. Epub 2022 Mar 25. Science. 2022. PMID: 35324283
New Insights into the Structure and Function of Class B1 GPCRs.
Cary BP, Zhang X, Cao J, Johnson RM, Piper SJ, Gerrard EJ, Wootten D, Sexton PM. Cary BP, et al. Among authors: johnson rm. Endocr Rev. 2023 May 8;44(3):492-517. doi: 10.1210/endrev/bnac033. Endocr Rev. 2023. PMID: 36546772 Free PMC article.
Emerging Role of Electron Microscopy in Drug Discovery.
Johnson RM, Higgins AJ, Muench SP. Johnson RM, et al. Trends Biochem Sci. 2019 Oct;44(10):897-898. doi: 10.1016/j.tibs.2019.07.003. Epub 2019 Aug 10. Trends Biochem Sci. 2019. PMID: 31409563 Free article. Review. No abstract available.
Approaches to altering particle distributions in cryo-electron microscopy sample preparation.
Drulyte I, Johnson RM, Hesketh EL, Hurdiss DL, Scarff CA, Porav SA, Ranson NA, Muench SP, Thompson RF. Drulyte I, et al. Among authors: johnson rm. Acta Crystallogr D Struct Biol. 2018 Jun 1;74(Pt 6):560-571. doi: 10.1107/S2059798318006496. Epub 2018 May 18. Acta Crystallogr D Struct Biol. 2018. PMID: 29872006 Free PMC article. Review.
755 results