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Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy.
Poh AR, Love CG, Chisanga D, Steer JH, Baloyan D, Chopin M, Nutt S, Rautela J, Huntington ND, Etemadi N, O'Brien M, O'Keefe R, Ellies LG, Macri C, Mintern JD, Whitehead L, Gangadhara G, Boon L, Chand AL, Lowell CA, Shi W, Pixley FJ, Ernst M. Poh AR, et al. Sci Adv. 2022 Jun 24;8(25):eabl7882. doi: 10.1126/sciadv.abl7882. Epub 2022 Jun 22. Sci Adv. 2022. PMID: 35731867 Free PMC article.
HER2 expression identifies dynamic functional states within circulating breast cancer cells.
Jordan NV, Bardia A, Wittner BS, Benes C, Ligorio M, Zheng Y, Yu M, Sundaresan TK, Licausi JA, Desai R, O'Keefe RM, Ebright RY, Boukhali M, Sil S, Onozato ML, Iafrate AJ, Kapur R, Sgroi D, Ting DT, Toner M, Ramaswamy S, Haas W, Maheswaran S, Haber DA. Jordan NV, et al. Nature. 2016 Sep 1;537(7618):102-106. doi: 10.1038/nature19328. Epub 2016 Aug 24. Nature. 2016. PMID: 27556950 Free PMC article.
Clusters of circulating tumor cells traverse capillary-sized vessels.
Au SH, Storey BD, Moore JC, Tang Q, Chen YL, Javaid S, Sarioglu AF, Sullivan R, Madden MW, O'Keefe R, Haber DA, Maheswaran S, Langenau DM, Stott SL, Toner M. Au SH, et al. Proc Natl Acad Sci U S A. 2016 May 3;113(18):4947-52. doi: 10.1073/pnas.1524448113. Epub 2016 Apr 18. Proc Natl Acad Sci U S A. 2016. PMID: 27091969 Free PMC article.
AR Expression in Breast Cancer CTCs Associates with Bone Metastases.
Aceto N, Bardia A, Wittner BS, Donaldson MC, O'Keefe R, Engstrom A, Bersani F, Zheng Y, Comaills V, Niederhoffer K, Zhu H, Mackenzie O, Shioda T, Sgroi D, Kapur R, Ting DT, Moy B, Ramaswamy S, Toner M, Haber DA, Maheswaran S. Aceto N, et al. Mol Cancer Res. 2018 Apr;16(4):720-727. doi: 10.1158/1541-7786.MCR-17-0480. Epub 2018 Feb 16. Mol Cancer Res. 2018. PMID: 29453314 Free PMC article.
Hind limb ischemia-reperfusion injury in diet-induced obese mice.
Albadawi H, Oklu R, Cormier NR, O'Keefe RM, Heaton JT, Kobler JB, Austen WG, Watkins MT. Albadawi H, et al. J Surg Res. 2014 Aug;190(2):683-91. doi: 10.1016/j.jss.2014.01.020. Epub 2014 Jan 17. J Surg Res. 2014. PMID: 24655666 Free PMC article.
464 results