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PKN2 deficiency leads both to prenatal 'congenital' cardiomyopathy and defective angiotensin II stress responses.
Marshall JJT, Cull JJ, Alharbi HO, Zaw Thin M, Cooper STE, Barrington C, Vanyai H, Snoeks T, Siow B, Suáarez-Bonnet A, Herbert E, Stuckey DJ, Cameron AJM, Prin F, Cook AC, Priestnall SL, Chotani S, Rackham OJL, Meijles DN, Mohun T, Clerk A, Parker PJ. Marshall JJT, et al. Biochem J. 2022 Jul 15;479(13):1467-1486. doi: 10.1042/BCJ20220281. Biochem J. 2022. PMID: 35730579 Free PMC article.
Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion.
Quétier I, Marshall JJT, Spencer-Dene B, Lachmann S, Casamassima A, Franco C, Escuin S, Worrall JT, Baskaran P, Rajeeve V, Howell M, Copp AJ, Stamp G, Rosewell I, Cutillas P, Gerhardt H, Parker PJ, Cameron AJM. Quétier I, et al. Among authors: marshall jjt. Cell Rep. 2016 Jan 26;14(3):440-448. doi: 10.1016/j.celrep.2015.12.049. Epub 2016 Jan 7. Cell Rep. 2016. PMID: 26774483 Free PMC article.
Uncoupling TORC2 from AGC kinases inhibits tumour growth.
Cameron AJM, Veeriah S, Marshall JJT, Murray ER, Larijani B, Parker PJ. Cameron AJM, et al. Among authors: marshall jjt. Oncotarget. 2017 Aug 9;8(49):84685-84696. doi: 10.18632/oncotarget.20086. eCollection 2017 Oct 17. Oncotarget. 2017. PMID: 29156676 Free PMC article.
A cancer-associated, genome protective programme engaging PKCε.
Parker PJ, Lockwood N, Davis K, Kelly JR, Soliman TN, Pardo AL, Marshall JJT, Redmond JM, Vitale M, Silvia Martini. Parker PJ, et al. Among authors: marshall jjt. Adv Biol Regul. 2020 Dec;78:100759. doi: 10.1016/j.jbior.2020.100759. Epub 2020 Oct 7. Adv Biol Regul. 2020. PMID: 33039823 Free PMC article. Review.
Equivocal, explicit and emergent actions of PKC isoforms in cancer.
Parker PJ, Brown SJ, Calleja V, Chakravarty P, Cobbaut M, Linch M, Marshall JJT, Martini S, McDonald NQ, Soliman T, Watson L. Parker PJ, et al. Among authors: marshall jjt. Nat Rev Cancer. 2021 Jan;21(1):51-63. doi: 10.1038/s41568-020-00310-4. Epub 2020 Nov 11. Nat Rev Cancer. 2021. PMID: 33177705 Review.
Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion.
Murray ER, Menezes S, Henry JC, Williams JL, Alba-Castellón L, Baskaran P, Quétier I, Desai A, Marshall JJT, Rosewell I, Tatari M, Rajeeve V, Khan F, Wang J, Kotantaki P, Tyler EJ, Singh N, Reader CS, Carter EP, Hodivala-Dilke K, Grose RP, Kocher HM, Gavara N, Pearce O, Cutillas P, Marshall JF, Cameron AJM. Murray ER, et al. Among authors: marshall jjt. Cell Rep. 2022 Jan 25;38(4):110227. doi: 10.1016/j.celrep.2021.110227. Cell Rep. 2022. PMID: 35081338 Free PMC article.
15 results