Lavallée JF - Search Results

1

Discovery of Two Novel Antiplatelet Clinical Candidates (BMS-986120 and BMS-986141) That Antagonize Protease-Activated Receptor 4.

Priestley ES, Banville J, Deon D, Dubé L, Gagnon M, Guy J, Lapointe P, Lavallée JF, Martel A, Plamondon S, Rémillard R, Ruediger E, Tremblay F, Posy SL, Guarino VR, Richter JM, Li J, Gupta A, Vetrichelvan M, Balapragalathan TJ, Mathur A, Hua J, Callejo M, Guay J, Sum CS, Cvijic ME, Watson C, Wong P, Yang J, Bouvier M, Gordon DA, Wexler RR, Marinier A. Priestley ES, et al. Among authors: lavallee jf. J Med Chem. 2022 Jul 14;65(13):8843-8854. doi: 10.1021/acs.jmedchem.2c00359. Epub 2022 Jun 21. J Med Chem. 2022. PMID: 35729784

2

Discovery of Potent Protease-Activated Receptor 4 Antagonists with in Vivo Antithrombotic Efficacy.

Miller MM, Banville J, Friends TJ, Gagnon M, Hangeland JJ, Lavallée JF, Martel A, O'Grady H, Rémillard R, Ruediger E, Tremblay F, Posy SL, Allegretto NJ, Guarino VR, Harden DG, Harper TW, Hartl K, Josephs J, Malmstrom S, Watson C, Yang Y, Zhang G, Wong P, Yang J, Bouvier M, Seiffert DA, Wexler RR, Lawrence RM, Priestley ES, Marinier A. Miller MM, et al. Among authors: lavallee jf. J Med Chem. 2019 Aug 22;62(16):7400-7416. doi: 10.1021/acs.jmedchem.9b00186. Epub 2019 Aug 5. J Med Chem. 2019. PMID: 31246024

3

Identification of Polo-like kinase 1 interaction inhibitors using a novel cell-based assay.

Normandin K, Lavallée JF, Futter M, Beautrait A, Duchaine J, Guiral S, Marinier A, Archambault V. Normandin K, et al. Among authors: lavallee jf. Sci Rep. 2016 Nov 22;5:37581. doi: 10.1038/srep37581. Sci Rep. 2016. PMID: 27874094 Free PMC article.

4

Discovery of 1,6-naphthyridines as a novel class of potent and selective human cytomegalovirus inhibitors.

Chan L, Jin H, Stefanac T, Lavallée JF, Falardeau G, Wang W, Bédard J, May S, Yuen L. Chan L, et al. Among authors: lavallee jf. J Med Chem. 1999 Aug 12;42(16):3023-5. doi: 10.1021/jm9902483. J Med Chem. 1999. PMID: 10447945 No abstract available.

5

Isoquinoline-6-carboxamides as potent and selective anti-human cytomegalovirus (HCMV) inhibitors.

Chan L, Jin H, Stefanac T, Wang W, Lavallée JF, Bédard J, May S. Chan L, et al. Among authors: lavallee jf. Bioorg Med Chem Lett. 1999 Sep 6;9(17):2583-6. doi: 10.1016/s0960-894x(99)00435-7. Bioorg Med Chem Lett. 1999. PMID: 10498213

6

Pyrido [1,2a] indole derivatives identified as novel non-nucleoside reverse transcriptase inhibitors of human immunodeficiency virus type 1.

Taylor DL, Ahmed PS, Chambers P, Tyms AS, Bedard J, Duchaine J, Falardeau G, Lavallée JF, Brown W, Rando RF, Bowlin T. Taylor DL, et al. Among authors: lavallee jf. Antivir Chem Chemother. 1999 Mar;10(2):79-86. doi: 10.1177/095632029901000204. Antivir Chem Chemother. 1999. PMID: 10335402 Free article.

7

Design and synthesis of new potent human cytomegalovirus (HCMV) inhibitors based on internally hydrogen-bonded 1,6-naphthyridines.

Chan L, Stefanac T, Lavallée JF, Jin H, Bédard J, May S, Falardeau G. Chan L, et al. Among authors: lavallee jf. Bioorg Med Chem Lett. 2001 Jan 22;11(2):103-5. doi: 10.1016/s0960-894x(00)00607-7. Bioorg Med Chem Lett. 2001. PMID: 11206437

8

Synthesis and structure--activity relationship of novel aminotetralin derivatives with high micro selective opioid affinity.

Roy C, Li T, Krasik P, Gilbert MJ, Pelletier C, Gagnon D, Robert E, Ducharme J, Storer R, Lavallée JF. Roy C, et al. Among authors: lavallee jf. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3141-3. doi: 10.1016/s0960-894x(02)00644-3. Bioorg Med Chem Lett. 2002. PMID: 12372519

9

Substituted 1,6-naphthyridines as human cytomegalovirus inhibitors: conformational requirements.

Falardeau G, Chan L, Stefanac T, May S, Jin H, Lavallée JF. Falardeau G, et al. Among authors: lavallee jf. Bioorg Med Chem Lett. 2000 Dec 18;10(24):2769-70. doi: 10.1016/s0960-894x(00)00568-0. Bioorg Med Chem Lett. 2000. PMID: 11133087

10

Lysine sulfonamides as novel HIV-protease inhibitors: Nepsilon-acyl aromatic alpha-amino acids.

Stranix BR, Lavallée JF, Sévigny G, Yelle J, Perron V, LeBerre N, Herbart D, Wu JJ. Stranix BR, et al. Among authors: lavallee jf. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3459-62. doi: 10.1016/j.bmcl.2006.04.011. Epub 2006 Apr 27. Bioorg Med Chem Lett. 2006. PMID: 16644213

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