Loreto A - Search Results

1

Cultured dissociated primary dorsal root ganglion neurons from adult horses enable study of axonal transport.

Adalbert R, Cahalan S, Hopkins EL, Almuhanna A, Loreto A, Pór E, Körmöczy L, Perkins J, Coleman MP, Piercy RJ. Adalbert R, et al. Among authors: loreto a. J Anat. 2022 Nov;241(5):1211-1218. doi: 10.1111/joa.13719. Epub 2022 Jun 21. J Anat. 2022. PMID: 35728923 Free PMC article.

2

NMN Deamidase Delays Wallerian Degeneration and Rescues Axonal Defects Caused by NMNAT2 Deficiency In Vivo.

Di Stefano M, Loreto A, Orsomando G, Mori V, Zamporlini F, Hulse RP, Webster J, Donaldson LF, Gering M, Raffaelli N, Coleman MP, Gilley J, Conforti L. Di Stefano M, et al. Among authors: loreto a. Curr Biol. 2017 Mar 20;27(6):784-794. doi: 10.1016/j.cub.2017.01.070. Epub 2017 Mar 2. Curr Biol. 2017. PMID: 28262487 Free article.

3

Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss.

White MA, Lin Z, Kim E, Henstridge CM, Pena Altamira E, Hunt CK, Burchill E, Callaghan I, Loreto A, Brown-Wright H, Mead R, Simmons C, Cash D, Coleman MP, Sreedharan J. White MA, et al. Among authors: loreto a. Acta Neuropathol Commun. 2019 Oct 28;7(1):166. doi: 10.1186/s40478-019-0800-9. Acta Neuropathol Commun. 2019. PMID: 31661035 Free PMC article.

4

Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration.

Loreto A, Hill CS, Hewitt VL, Orsomando G, Angeletti C, Gilley J, Lucci C, Sanchez-Martinez A, Whitworth AJ, Conforti L, Dajas-Bailador F, Coleman MP. Loreto A, et al. Neurobiol Dis. 2020 Feb;134:104678. doi: 10.1016/j.nbd.2019.104678. Epub 2019 Nov 15. Neurobiol Dis. 2020. PMID: 31740269 Free PMC article.

5

Novel HDAC6 Inhibitors Increase Tubulin Acetylation and Rescue Axonal Transport of Mitochondria in a Model of Charcot-Marie-Tooth Type 2F.

Adalbert R, Kaieda A, Antoniou C, Loreto A, Yang X, Gilley J, Hoshino T, Uga K, Makhija MT, Coleman MP. Adalbert R, et al. Among authors: loreto a. ACS Chem Neurosci. 2020 Feb 5;11(3):258-267. doi: 10.1021/acschemneuro.9b00338. Epub 2020 Jan 8. ACS Chem Neurosci. 2020. PMID: 31845794 Free PMC article.

6

Loss of highwire Protects Against the Deleterious Effects of Traumatic Brain Injury in Drosophila Melanogaster.

Hill CS, Sreedharan J, Loreto A, Menon DK, Coleman MP. Hill CS, et al. Among authors: loreto a. Front Neurol. 2020 May 12;11:401. doi: 10.3389/fneur.2020.00401. eCollection 2020. Front Neurol. 2020. PMID: 32477254 Free PMC article.

7

Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity.

Mabbitt PD, Loreto A, Déry MA, Fletcher AJ, Stanley M, Pao KC, Wood NT, Coleman MP, Virdee S. Mabbitt PD, et al. Among authors: loreto a. Nat Chem Biol. 2020 Nov;16(11):1227-1236. doi: 10.1038/s41589-020-0598-6. Epub 2020 Aug 3. Nat Chem Biol. 2020. PMID: 32747811 Free PMC article.

8

Mitochondrial dysfunction as a trigger of programmed axon death.

Merlini E, Coleman MP, Loreto A. Merlini E, et al. Among authors: loreto a. Trends Neurosci. 2022 Jan;45(1):53-63. doi: 10.1016/j.tins.2021.10.014. Epub 2021 Nov 29. Trends Neurosci. 2022. PMID: 34852932 Review.

9

Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1.

Loreto A, Angeletti C, Gu W, Osborne A, Nieuwenhuis B, Gilley J, Merlini E, Arthur-Farraj P, Amici A, Luo Z, Hartley-Tassell L, Ve T, Desrochers LM, Wang Q, Kobe B, Orsomando G, Coleman MP. Loreto A, et al. Elife. 2021 Dec 6;10:e72823. doi: 10.7554/eLife.72823. Elife. 2021. PMID: 34870595 Free PMC article.

10

SARM1 is a multi-functional NAD(P)ase with prominent base exchange activity, all regulated bymultiple physiologically relevant NAD metabolites.

Angeletti C, Amici A, Gilley J, Loreto A, Trapanotto AG, Antoniou C, Merlini E, Coleman MP, Orsomando G. Angeletti C, et al. Among authors: loreto a. iScience. 2022 Jan 25;25(2):103812. doi: 10.1016/j.isci.2022.103812. eCollection 2022 Feb 18. iScience. 2022. PMID: 35198877 Free PMC article.

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