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COVID-19 and Preexisting Comorbidities: Risks, Synergies, and Clinical Outcomes.
Bigdelou B, Sepand MR, Najafikhoshnoo S, Negrete JAT, Sharaf M, Ho JQ, Sullivan I, Chauhan P, Etter M, Shekarian T, Liang O, Hutter G, Esfandiarpour R, Zanganeh S. Bigdelou B, et al. Among authors: liang o. Front Immunol. 2022 May 27;13:890517. doi: 10.3389/fimmu.2022.890517. eCollection 2022. Front Immunol. 2022. PMID: 35711466 Free PMC article. Review.
LRRC15 inhibits SARS-CoV-2 cellular entry in trans.
Song J, Chow RD, Peña-Hernández MA, Zhang L, Loeb SA, So EY, Liang OD, Ren P, Chen S, Wilen CB, Lee S. Song J, et al. PLoS Biol. 2022 Oct 13;20(10):e3001805. doi: 10.1371/journal.pbio.3001805. eCollection 2022 Oct. PLoS Biol. 2022. PMID: 36228039 Free PMC article.
Natural Killer cell activation, reduced ACE2, TMPRSS2, cytokines G-CSF, M-CSF and SARS-CoV-2-S pseudovirus infectivity by MEK inhibitor treatment of human cells.
Zhou L, Huntington K, Zhang S, Carlsen L, So EY, Parker C, Sahin I, Safran H, Kamle S, Lee CM, Lee CG, Elias JA, Campbell KS, Naik MT, Atwood WJ, Youssef E, Pachter JA, Navaraj A, Seyhan AA, Liang O, El-Deiry WS. Zhou L, et al. Among authors: liang o. bioRxiv [Preprint]. 2020 Sep 2:2020.08.02.230839. doi: 10.1101/2020.08.02.230839. bioRxiv. 2020. PMID: 32793908 Free PMC article. Preprint.
MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection.
Zhou L, Huntington K, Zhang S, Carlsen L, So EY, Parker C, Sahin I, Safran H, Kamle S, Lee CM, Geun Lee C, A Elias J, S Campbell K, T Naik M, J Atwood W, Youssef E, A Pachter J, Navaraj A, A Seyhan A, Liang O, El-Deiry WS. Zhou L, et al. Among authors: liang o. Oncotarget. 2020 Nov 17;11(46):4201-4223. doi: 10.18632/oncotarget.27799. eCollection 2020 Nov 17. Oncotarget. 2020. PMID: 33245731 Free PMC article.
Chitinase 3-like-1 is a Therapeutic Target That Mediates the Effects of Aging in COVID-19.
Kamle S, Ma B, He CH, Akosman B, Zhou Y, Lee CM, El-Deiry WS, Huntington K, Liang O, Machan JT, Kang MJ, Shin HJ, Mizoguchi E, Lee CG, Elias JA. Kamle S, et al. Among authors: liang o. bioRxiv [Preprint]. 2021 Feb 16:2021.01.05.425478. doi: 10.1101/2021.01.05.425478. bioRxiv. 2021. PMID: 33442679 Free PMC article. Updated. Preprint.
106 results