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Drug-like Inhibitors of DC-SIGN Based on a Quinolone Scaffold.
Zhang H, Daněk O, Makarov D, Rádl S, Kim D, Ledvinka J, Vychodilová K, Hlaváč J, Lefèbre J, Denis M, Rademacher C, Ménová P. Zhang H, et al. Among authors: rademacher c. ACS Med Chem Lett. 2022 May 10;13(6):935-942. doi: 10.1021/acsmedchemlett.2c00067. eCollection 2022 Jun 9. ACS Med Chem Lett. 2022. PMID: 35707152 Free PMC article.
Allosteric Inhibition of a Mammalian Lectin.
Aretz J, Anumala UR, Fuchsberger FF, Molavi N, Ziebart N, Zhang H, Nazaré M, Rademacher C. Aretz J, et al. Among authors: rademacher c. J Am Chem Soc. 2018 Nov 7;140(44):14915-14925. doi: 10.1021/jacs.8b08644. Epub 2018 Oct 24. J Am Chem Soc. 2018. PMID: 30303367
The 3F Library: Fluorinated Fsp3 -Rich Fragments for Expeditious 19 F NMR Based Screening.
Troelsen NS, Shanina E, Gonzalez-Romero D, Danková D, Jensen ISA, Śniady KJ, Nami F, Zhang H, Rademacher C, Cuenda A, Gotfredsen CH, Clausen MH. Troelsen NS, et al. Among authors: rademacher c. Angew Chem Int Ed Engl. 2020 Feb 3;59(6):2204-2210. doi: 10.1002/anie.201913125. Epub 2019 Dec 17. Angew Chem Int Ed Engl. 2020. PMID: 31724281
Protein-observed 19F NMR of LecA from Pseudomonas aeruginosa.
Shanina E, Siebs E, Zhang H, Varón Silva D, Joachim I, Titz A, Rademacher C. Shanina E, et al. Among authors: rademacher c. Glycobiology. 2021 Feb 9;31(2):159-165. doi: 10.1093/glycob/cwaa057. Glycobiology. 2021. PMID: 32573695 Free PMC article.
Rational Design of a DNA-Scaffolded High-Affinity Binder for Langerin.
Bachem G, Wamhoff EC, Silberreis K, Kim D, Baukmann H, Fuchsberger F, Dernedde J, Rademacher C, Seitz O. Bachem G, et al. Among authors: rademacher c. Angew Chem Int Ed Engl. 2020 Nov 16;59(47):21016-21022. doi: 10.1002/anie.202006880. Epub 2020 Sep 15. Angew Chem Int Ed Engl. 2020. PMID: 32749019 Free PMC article.
From Pyrazolones to Azaindoles: Evolution of Active-Site SHP2 Inhibitors Based on Scaffold Hopping and Bioisosteric Replacement.
Mostinski Y, Heynen GJJE, López-Alberca MP, Paul J, Miksche S, Radetzki S, Schaller D, Shanina E, Seyffarth C, Kolomeets Y, Ziebart N, de Schryver J, Oestreich S, Neuenschwander M, Roske Y, Heinemann U, Rademacher C, Volkamer A, von Kries JP, Birchmeier W, Nazaré M. Mostinski Y, et al. Among authors: rademacher c. J Med Chem. 2020 Dec 10;63(23):14780-14804. doi: 10.1021/acs.jmedchem.0c01265. Epub 2020 Nov 19. J Med Chem. 2020. PMID: 33210922
154 results