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Population pharmacokinetics of cabotegravir following administration of oral tablet and long-acting intramuscular injection in adult HIV-1-infected and uninfected subjects.
Han K, Baker M, Lovern M, Paul P, Xiong Y, Patel P, Moore KP, Seal CS, Cutrell AG, D'Amico RD, Benn PD, Landovitz RJ, Marzinke MA, Spreen WR, Ford SL. Han K, et al. Among authors: spreen wr. Br J Clin Pharmacol. 2022 Oct;88(10):4607-4622. doi: 10.1111/bcp.15439. Epub 2022 Jul 4. Br J Clin Pharmacol. 2022. PMID: 35695476 Free PMC article.
A long-acting integrase inhibitor protects female macaques from repeated high-dose intravaginal SHIV challenge.
Andrews CD, Yueh YL, Spreen WR, St Bernard L, Boente-Carrera M, Rodriguez K, Gettie A, Russell-Lodrigue K, Blanchard J, Ford S, Mohri H, Cheng-Mayer C, Hong Z, Ho DD, Markowitz M. Andrews CD, et al. Among authors: spreen wr. Sci Transl Med. 2015 Jan 14;7(270):270ra4. doi: 10.1126/scitranslmed.3010298. Sci Transl Med. 2015. PMID: 25589630 Free PMC article.
Formulation and pharmacology of long-acting cabotegravir.
Trezza C, Ford SL, Spreen W, Pan R, Piscitelli S. Trezza C, et al. Curr Opin HIV AIDS. 2015 Jul;10(4):239-45. doi: 10.1097/COH.0000000000000168. Curr Opin HIV AIDS. 2015. PMID: 26049948 Free PMC article. Review.
Disposition and metabolism of cabotegravir: a comparison of biotransformation and excretion between different species and routes of administration in humans.
Bowers GD, Culp A, Reese MJ, Tabolt G, Moss L, Piscitelli S, Huynh P, Wagner D, Ford SL, Gould EP, Pan R, Lou Y, Margolis DA, Spreen WR. Bowers GD, et al. Among authors: spreen wr. Xenobiotica. 2016;46(2):147-62. doi: 10.3109/00498254.2015.1060372. Epub 2015 Jul 1. Xenobiotica. 2016. PMID: 26134155 Clinical Trial.
81 results