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Calibration and Validation of a Mechanistic COVID-19 Model for Translational Quantitative Systems Pharmacology - A Proof-of-Concept Model Development for Remdesivir.
Samieegohar M, Weaver JL, Howard KE, Chaturbedi A, Mann J, Han X, Zirkle J, Arabidarrehdor G, Rouse R, Florian J, Strauss DG, Li Z. Samieegohar M, et al. Among authors: strauss dg. Clin Pharmacol Ther. 2022 Oct;112(4):882-891. doi: 10.1002/cpt.2686. Epub 2022 Jun 29. Clin Pharmacol Ther. 2022. PMID: 35694844 Free PMC article.
Differentiating drug-induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine, and verapamil.
Johannesen L, Vicente J, Mason JW, Sanabria C, Waite-Labott K, Hong M, Guo P, Lin J, Sørensen JS, Galeotti L, Florian J, Ugander M, Stockbridge N, Strauss DG. Johannesen L, et al. Among authors: strauss dg. Clin Pharmacol Ther. 2014 Nov;96(5):549-58. doi: 10.1038/clpt.2014.155. Epub 2014 Jul 23. Clin Pharmacol Ther. 2014. PMID: 25054430 Clinical Trial.
Late sodium current block for drug-induced long QT syndrome: Results from a prospective clinical trial.
Johannesen L, Vicente J, Mason JW, Erato C, Sanabria C, Waite-Labott K, Hong M, Lin J, Guo P, Mutlib A, Wang J, Crumb WJ, Blinova K, Chan D, Stohlman J, Florian J, Ugander M, Stockbridge N, Strauss DG. Johannesen L, et al. Among authors: strauss dg. Clin Pharmacol Ther. 2016 Feb;99(2):214-23. doi: 10.1002/cpt.205. Epub 2015 Nov 28. Clin Pharmacol Ther. 2016. PMID: 26259627 Free PMC article. Clinical Trial.
Mechanistic Model-Informed Proarrhythmic Risk Assessment of Drugs: Review of the "CiPA" Initiative and Design of a Prospective Clinical Validation Study.
Vicente J, Zusterzeel R, Johannesen L, Mason J, Sager P, Patel V, Matta MK, Li Z, Liu J, Garnett C, Stockbridge N, Zineh I, Strauss DG. Vicente J, et al. Among authors: strauss dg. Clin Pharmacol Ther. 2018 Jan;103(1):54-66. doi: 10.1002/cpt.896. Epub 2017 Nov 16. Clin Pharmacol Ther. 2018. PMID: 28986934 Free PMC article. Review.
185 results