El-Ashrey MK - Search Results

1

Biological Evaluation, Molecular Docking Analyses, and ADME Profiling of Certain New Quinazolinones as Anti-colorectal Agents.

El-Sayed NNE, Almaneai NM, Ben Bacha A, El-Ashrey MK, Al-Zaben MI, Almarhoon ZM. El-Sayed NNE, et al. ACS Omega. 2022 May 23;7(22):18443-18458. doi: 10.1021/acsomega.2c00812. eCollection 2022 Jun 7. ACS Omega. 2022. PMID: 35694504 Free PMC article.

2

Synthesis, Biological, and Molecular Docking Studies on 4,5,6,7-Tetrahydrobenzo[b]thiophene Derivatives and Their Nanoparticles Targeting Colorectal Cancer.

Kamal S, Derbala HA, Alterary SS, Ben Bacha A, Alonazi M, El-Ashrey MK, Eid El-Sayed NN. Kamal S, et al. ACS Omega. 2021 Oct 25;6(43):28992-29008. doi: 10.1021/acsomega.1c04063. eCollection 2021 Nov 2. ACS Omega. 2021. PMID: 34746589 Free PMC article.

3

Novel Pyridothienopyrimidine Derivatives: Design, Synthesis and Biological Evaluation as Antimicrobial and Anticancer Agents.

Mohi El-Deen EM, Anwar MM, El-Gwaad AAA, Karam EA, El-Ashrey MK, Kassab RR. Mohi El-Deen EM, et al. Molecules. 2022 Jan 26;27(3):803. doi: 10.3390/molecules27030803. Molecules. 2022. PMID: 35164067 Free PMC article.

4

1-Benzyl-5-bromo-3-hydrazonoindolin-2-ones as Novel Anticancer Agents: Synthesis, Biological Evaluation and Molecular Modeling Insights.

Al-Warhi T, Almahli H, Maklad RM, Elsayed ZM, El Hassab MA, Alotaibi OJ, Aljaeed N, Ayyad RR, Ghabour HA, Eldehna WM, El-Ashrey MK. Al-Warhi T, et al. Molecules. 2023 Apr 4;28(7):3203. doi: 10.3390/molecules28073203. Molecules. 2023. PMID: 37049966 Free PMC article.

5

Insights into targeting SARS-CoV-2: design, synthesis, in silico studies and antiviral evaluation of new dimethylxanthine derivatives.

Mohamed AR, Mostafa A, El Hassab MA, Hedeab GM, Mahmoud SH, George RF, Georgey HH, Abdel Gawad NM, El-Ashrey MK. Mohamed AR, et al. RSC Med Chem. 2023 Mar 21;14(5):899-920. doi: 10.1039/d3md00056g. eCollection 2023 May 25. RSC Med Chem. 2023. PMID: 37252103 Free PMC article.

6

Discovery of pyrimidine-tethered benzothiazole derivatives as novel anti-tubercular agents towards multi- and extensively drug resistant Mycobacterium tuberculosis.

Hemeda LR, El Hassab MA, Abdelgawad MA, Khaleel EF, Abdel-Aziz MM, Binjubair FA, Al-Rashood ST, Eldehna WM, El-Ashrey MK. Hemeda LR, et al. Among authors: el ashrey mk. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2250575. doi: 10.1080/14756366.2023.2250575. J Enzyme Inhib Med Chem. 2023. PMID: 37649381 Free PMC article.

7

Synthesis and molecular docking of new roflumilast analogues as preferential-selective potent PDE-4B inhibitors with improved pharmacokinetic profile.

Moussa BA, El-Zaher AA, El-Ashrey MK, Fouad MA. Moussa BA, et al. Eur J Med Chem. 2018 Mar 25;148:477-486. doi: 10.1016/j.ejmech.2018.02.038. Epub 2018 Feb 17. Eur J Med Chem. 2018. PMID: 29477888

8

Pharmacophore based virtual screening for natural product database revealed possible inhibitors for SARS-COV-2 main protease.

El-Ashrey MK, Bakr RO, Fayed MAA, Refaey RH, Nissan YM. El-Ashrey MK, et al. Virology. 2022 May;570:18-28. doi: 10.1016/j.virol.2022.03.003. Epub 2022 Mar 22. Virology. 2022. PMID: 35339903 Free PMC article.

9

Alanine racemase a promising Helicobacter pylori drug target inhibited by propanoic acid.

Ibrahim KA, El-Ashrey MK, Kashef MT, Helmy OM. Ibrahim KA, et al. Among authors: el ashrey mk. Microbes Infect. 2023 Sep-Oct;25(7):105167. doi: 10.1016/j.micinf.2023.105167. Epub 2023 Jun 2. Microbes Infect. 2023. PMID: 37271368

10

Repurposing of renin inhibitors as SARS-COV-2 main protease inhibitors: A computational study.

Refaey RH, El-Ashrey MK, Nissan YM. Refaey RH, et al. Virology. 2021 Feb;554:48-54. doi: 10.1016/j.virol.2020.12.008. Epub 2020 Dec 24. Virology. 2021. PMID: 33370597 Free PMC article.

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