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Nanoemulsion of Sideroxylon obtusifolium as an Alternative to Combat Schistosomiasis.
Rangel LDS, Passos de Oliveira A, Falcão DQ, Santos MG, Von Ranke NL, Rodrigues CR, Dos Santos JAA, Rocha L, Faria RX. Rangel LDS, et al. Among authors: faria rx. Front Plant Sci. 2022 May 26;13:853002. doi: 10.3389/fpls.2022.853002. eCollection 2022. Front Plant Sci. 2022. PMID: 35693155 Free PMC article.
1-Aryl-1H- and 2-aryl-2H-1,2,3-triazole derivatives blockade P2X7 receptor in vitro and inflammatory response in vivo.
Gonzaga DTG, Ferreira LBG, Moreira Maramaldo Costa TE, von Ranke NL, Anastácio Furtado Pacheco P, Sposito Simões AP, Arruda JC, Dantas LP, de Freitas HR, de Melo Reis RA, Penido C, Bello ML, Castro HC, Rodrigues CR, Ferreira VF, Faria RX, da Silva FC. Gonzaga DTG, et al. Among authors: faria rx. Eur J Med Chem. 2017 Oct 20;139:698-717. doi: 10.1016/j.ejmech.2017.08.034. Epub 2017 Aug 16. Eur J Med Chem. 2017. PMID: 28858765
1,4-Naphthoquinones potently inhibiting P2X7 receptor activity.
Faria RX, Oliveira FH, Salles JP, Oliveira AS, von Ranke NL, Bello ML, Rodrigues CR, Castro HC, Louvis AR, Martins DL, Ferreira VF. Faria RX, et al. Eur J Med Chem. 2018 Jan 1;143:1361-1372. doi: 10.1016/j.ejmech.2017.10.033. Epub 2017 Oct 23. Eur J Med Chem. 2018. PMID: 29133043
8-Hydroxy-2-(1H-1,2,3-triazol-1-yl)-1,4-naphtoquinone derivatives inhibited P2X7 Receptor-Induced dye uptake into murine Macrophages.
Pacheco PAF, Galvão RMS, Faria AFM, Von Ranke NL, Rangel MS, Ribeiro TM, Bello ML, Rodrigues CR, Ferreira VF, da Rocha DR, Faria RX. Pacheco PAF, et al. Among authors: faria rx, faria afm. Bioorg Med Chem. 2019 Apr 15;27(8):1449-1455. doi: 10.1016/j.bmc.2018.11.036. Epub 2018 Nov 27. Bioorg Med Chem. 2019. PMID: 30528164
Nanoemulsion containing essential oil from Xylopia ochrantha Mart. produces molluscicidal effects against different species of Biomphalaria (Schistosoma hosts).
Araújo FP, Albuquerque RDDG, Rangel LDS, Caldas GR, Tietbohl LAC, Santos MG, Ricci-Júnior E, Thiengo S, Fernandez MA, Santos JAAD, Faria RX, Rocha L. Araújo FP, et al. Among authors: faria rx. Mem Inst Oswaldo Cruz. 2019 Apr 8;114:e180489. doi: 10.1590/0074-02760180489. Mem Inst Oswaldo Cruz. 2019. PMID: 30970079 Free PMC article.
Synthesis, Biological Evaluation, and Molecular Modeling Studies of New Thiadiazole Derivatives as Potent P2X7 Receptor Inhibitors.
Gonzaga DTG, Oliveira FH, von Ranke NL, Pinho GQ, Salles JP, Bello ML, Rodrigues CR, Castro HC, de Souza HVCM, Reis CRC, Leme RPP, Mafra JCM, Pinheiro LCS, Hoelz LVB, Boechat N, Faria RX. Gonzaga DTG, et al. Among authors: faria rx. Front Chem. 2019 Apr 30;7:261. doi: 10.3389/fchem.2019.00261. eCollection 2019. Front Chem. 2019. PMID: 31134177 Free PMC article.
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