Morris JR - Search Results

1

A ferrocene-containing nucleoside analogue targets DNA replication in pancreatic cancer cells.

Rana M, Perotti A, Bisset LM, Smith JD, Lamden E, Khan Z, Ismail MK, Ellis K, Armstrong KA, Hodder SL, Bertoli C, Meneguello L, de Bruin RAM, Morris JR, Romero-Canelon I, Tucker JHR, Hodges NJ. Rana M, et al. Among authors: morris jr. Metallomics. 2022 Jul 25;14(7):mfac041. doi: 10.1093/mtomcs/mfac041. Metallomics. 2022. PMID: 35689667 Free PMC article.

2

A fork in the road: Where homologous recombination and stalled replication fork protection part ways.

Tye S, Ronson GE, Morris JR. Tye S, et al. Among authors: morris jr. Semin Cell Dev Biol. 2021 May;113:14-26. doi: 10.1016/j.semcdb.2020.07.004. Epub 2020 Jul 9. Semin Cell Dev Biol. 2021. PMID: 32653304 Free PMC article. Review.

3

Mechanisms of synthetic lethality between BRCA1/2 and 53BP1 deficiencies and DNA polymerase theta targeting.

Ronson GE, Starowicz K, Anthony EJ, Piberger AL, Clarke LC, Garvin AJ, Beggs AD, Whalley CM, Edmonds MJ, Beesley JFJ, Morris JR. Ronson GE, et al. Among authors: morris jr. Nat Commun. 2023 Nov 29;14(1):7834. doi: 10.1038/s41467-023-43677-2. Nat Commun. 2023. PMID: 38030626 Free PMC article.

4

BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair.

Morris JR, Solomon E. Morris JR, et al. Hum Mol Genet. 2004 Apr 15;13(8):807-17. doi: 10.1093/hmg/ddh095. Epub 2004 Feb 19. Hum Mol Genet. 2004. PMID: 14976165

5

The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response.

Butler LR, Densham RM, Jia J, Garvin AJ, Stone HR, Shah V, Weekes D, Festy F, Beesley J, Morris JR. Butler LR, et al. Among authors: morris jr. EMBO J. 2012 Oct 3;31(19):3918-34. doi: 10.1038/emboj.2012.232. Epub 2012 Aug 21. EMBO J. 2012. PMID: 22909820 Free PMC article.

6

DNA damage emergency: cellular garbage disposal to the rescue?

Stone HR, Morris JR. Stone HR, et al. Among authors: morris jr. Oncogene. 2014 Feb 13;33(7):805-13. doi: 10.1038/onc.2013.60. Epub 2013 Mar 18. Oncogene. 2014. PMID: 23503465 Review.

7

Human BRCA1-BARD1 ubiquitin ligase activity counteracts chromatin barriers to DNA resection.

Densham RM, Garvin AJ, Stone HR, Strachan J, Baldock RA, Daza-Martin M, Fletcher A, Blair-Reid S, Beesley J, Johal B, Pearl LH, Neely R, Keep NH, Watts FZ, Morris JR. Densham RM, et al. Among authors: morris jr. Nat Struct Mol Biol. 2016 Jul;23(7):647-55. doi: 10.1038/nsmb.3236. Epub 2016 May 30. Nat Struct Mol Biol. 2016. PMID: 27239795 Free PMC article.

8

USP48 restrains resection by site-specific cleavage of the BRCA1 ubiquitin mark from H2A.

Uckelmann M, Densham RM, Baas R, Winterwerp HHK, Fish A, Sixma TK, Morris JR. Uckelmann M, et al. Among authors: morris jr. Nat Commun. 2018 Jan 15;9(1):229. doi: 10.1038/s41467-017-02653-3. Nat Commun. 2018. PMID: 29335415 Free PMC article.

9

Isomerization of BRCA1-BARD1 promotes replication fork protection.

Daza-Martin M, Starowicz K, Jamshad M, Tye S, Ronson GE, MacKay HL, Chauhan AS, Walker AK, Stone HR, Beesley JFJ, Coles JL, Garvin AJ, Stewart GS, McCorvie TJ, Zhang X, Densham RM, Morris JR. Daza-Martin M, et al. Among authors: morris jr. Nature. 2019 Jul;571(7766):521-527. doi: 10.1038/s41586-019-1363-4. Epub 2019 Jul 3. Nature. 2019. PMID: 31270457

10

Is it a wrap? Nucleosome interactions of the BRCA1-binding partner, BARD1, steal the scene.

Morris JR. Morris JR. Nat Struct Mol Biol. 2021 Sep;28(9):708-710. doi: 10.1038/s41594-021-00658-7. Nat Struct Mol Biol. 2021. PMID: 34518696 No abstract available.

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