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An epigenome-wide view of osteoarthritis in primary tissues.
Kreitmaier P, Suderman M, Southam L, Coutinho de Almeida R, Hatzikotoulas K, Meulenbelt I, Steinberg J, Relton CL, Wilkinson JM, Zeggini E. Kreitmaier P, et al. Among authors: coutinho de almeida r. Am J Hum Genet. 2022 Jul 7;109(7):1255-1271. doi: 10.1016/j.ajhg.2022.05.010. Epub 2022 Jun 8. Am J Hum Genet. 2022. PMID: 35679866 Free PMC article.
RNA sequencing data integration reveals an miRNA interactome of osteoarthritis cartilage.
Coutinho de Almeida R, Ramos YFM, Mahfouz A, den Hollander W, Lakenberg N, Houtman E, van Hoolwerff M, Suchiman HED, Rodríguez Ruiz A, Slagboom PE, Mei H, Kiełbasa SM, Nelissen RGHH, Reinders M, Meulenbelt I. Coutinho de Almeida R, et al. Ann Rheum Dis. 2019 Feb;78(2):270-277. doi: 10.1136/annrheumdis-2018-213882. Epub 2018 Dec 1. Ann Rheum Dis. 2019. PMID: 30504444 Free PMC article.
Involvement of epigenetics in osteoarthritis.
Coutinho de Almeida R, Ramos YFM, Meulenbelt I. Coutinho de Almeida R, et al. Best Pract Res Clin Rheumatol. 2017 Oct;31(5):634-648. doi: 10.1016/j.berh.2018.03.002. Best Pract Res Clin Rheumatol. 2017. PMID: 30509410 Review.
Identification and characterization of two consistent osteoarthritis subtypes by transcriptome and clinical data integration.
Coutinho de Almeida R, Mahfouz A, Mei H, Houtman E, den Hollander W, Soul J, Suchiman E, Lakenberg N, Meessen J, Huetink K, Nelissen RGHH, Ramos YFM, Reinders M, Meulenbelt I. Coutinho de Almeida R, et al. Rheumatology (Oxford). 2021 Mar 2;60(3):1166-1175. doi: 10.1093/rheumatology/keaa391. Rheumatology (Oxford). 2021. PMID: 32885253 Free PMC article.
Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene.
Boer CG, Yau MS, Rice SJ, Coutinho de Almeida R, Cheung K, Styrkarsdottir U, Southam L, Broer L, Wilkinson JM, Uitterlinden AG, Zeggini E, Felson D, Loughlin J, Young M, Capellini TD, Meulenbelt I, van Meurs JB. Boer CG, et al. Among authors: coutinho de almeida r. Ann Rheum Dis. 2021 Mar;80(3):367-375. doi: 10.1136/annrheumdis-2020-217834. Epub 2020 Oct 14. Ann Rheum Dis. 2021. PMID: 33055079 Free PMC article.
RNA Sequencing Reveals Interacting Key Determinants of Osteoarthritis Acting in Subchondral Bone and Articular Cartilage: Identification of IL11 and CHADL as Attractive Treatment Targets.
Tuerlings M, van Hoolwerff M, Houtman E, Suchiman EHED, Lakenberg N, Mei H, van der Linden EHMJ, Nelissen RRGHH, Ramos YYFM, Coutinho de Almeida R, Meulenbelt I. Tuerlings M, et al. Among authors: coutinho de almeida r. Arthritis Rheumatol. 2021 May;73(5):789-799. doi: 10.1002/art.41600. Epub 2021 Mar 21. Arthritis Rheumatol. 2021. PMID: 33258547 Free PMC article.
Characterization of dynamic changes in Matrix Gla Protein (MGP) gene expression as function of genetic risk alleles, osteoarthritis relevant stimuli, and the vitamin K inhibitor warfarin.
Houtman E, Coutinho de Almeida R, Tuerlings M, Suchiman HED, Broekhuis D, Nelissen RGHH, Ramos YFM, van Meurs JBJ, Meulenbelt I. Houtman E, et al. Among authors: coutinho de almeida r. Osteoarthritis Cartilage. 2021 Aug;29(8):1193-1202. doi: 10.1016/j.joca.2021.05.001. Epub 2021 May 10. Osteoarthritis Cartilage. 2021. PMID: 33984465 Free article.
The role of TNFRSF11B in development of osteoarthritic cartilage.
Rodríguez Ruiz A, Tuerlings M, Das A, Coutinho de Almeida R, Suchiman HED, Nelissen RGHH, Ramos YFM, Meulenbelt I. Rodríguez Ruiz A, et al. Among authors: coutinho de almeida r. Rheumatology (Oxford). 2022 Feb 2;61(2):856-864. doi: 10.1093/rheumatology/keab440. Rheumatology (Oxford). 2022. PMID: 33989379 Free PMC article.
Elucidating mechano-pathology of osteoarthritis: transcriptome-wide differences in mechanically stressed aged human cartilage explants.
Houtman E, Tuerlings M, Riechelman J, Suchiman EHED, van der Wal RJP, Nelissen RGHH, Mei H, Ramos YFM, Coutinho de Almeida R, Meulenbelt I. Houtman E, et al. Among authors: coutinho de almeida r. Arthritis Res Ther. 2021 Aug 16;23(1):215. doi: 10.1186/s13075-021-02595-8. Arthritis Res Ther. 2021. PMID: 34399844 Free PMC article.
28 results