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Mature neutrophils and a NF-κB-to-IFN transition determine the unifying disease recovery dynamics in COVID-19.
Frishberg A, Kooistra E, Nuesch-Germano M, Pecht T, Milman N, Reusch N, Warnat-Herresthal S, Bruse N, Händler K, Theis H, Kraut M, van Rijssen E, van Cranenbroek B, Koenen HJ, Heesakkers H, van den Boogaard M, Zegers M, Pickkers P, Becker M, Aschenbrenner AC, Ulas T, Theis FJ, Shen-Orr SS, Schultze JL, Kox M. Frishberg A, et al. Among authors: shen orr ss. Cell Rep Med. 2022 Jun 21;3(6):100652. doi: 10.1016/j.xcrm.2022.100652. Epub 2022 May 17. Cell Rep Med. 2022. PMID: 35675822 Free PMC article.
Reconstructing disease dynamics for mechanistic insights and clinical benefit.
Frishberg A, Milman N, Alpert A, Spitzer H, Asani B, Schiefelbein JB, Bakin E, Regev-Berman K, Priglinger SG, Schultze JL, Theis FJ, Shen-Orr SS. Frishberg A, et al. Among authors: shen orr ss. Nat Commun. 2023 Oct 27;14(1):6840. doi: 10.1038/s41467-023-42354-8. Nat Commun. 2023. PMID: 37891175 Free PMC article.
B cell-derived cfDNA after primary BNT162b2 mRNA vaccination anticipates memory B cells and SARS-CoV-2 neutralizing antibodies.
Fox-Fisher I, Piyanzin S, Briller M, Oiknine-Djian E, Alfi O, Ben-Ami R, Peretz A, Neiman D, Ochana BL, Fridlich O, Drawshy Z, Klochendler A, Magenheim J, Share D, Avrahami R, Ribak Y, Talmon A, Rubin L, Milman N, Segev M, Feldman E, Tal Y, Shen-Orr SS, Glaser B, Shemer R, Wolf D, Dor Y. Fox-Fisher I, et al. Among authors: shen orr ss. Med. 2022 Jul 8;3(7):468-480.e5. doi: 10.1016/j.medj.2022.05.005. Epub 2022 May 19. Med. 2022. PMID: 35716665 Free PMC article.
Activation of the reward system boosts innate and adaptive immunity.
Ben-Shaanan TL, Azulay-Debby H, Dubovik T, Starosvetsky E, Korin B, Schiller M, Green NL, Admon Y, Hakim F, Shen-Orr SS, Rolls A. Ben-Shaanan TL, et al. Nat Med. 2016 Aug;22(8):940-4. doi: 10.1038/nm.4133. Epub 2016 Jul 4. Nat Med. 2016. PMID: 27376577
Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis.
Fujita Y, Khateb A, Li Y, Tinoco R, Zhang T, Bar-Yoseph H, Tam MA, Chowers Y, Sabo E, Gerassy-Vainberg S, Starosvetsky E, James B, Brown K, Shen-Orr SS, Bradley LM, Tessier PA, Ronai ZA. Fujita Y, et al. Cell Rep. 2018 Sep 18;24(12):3296-3311.e6. doi: 10.1016/j.celrep.2018.08.057. Cell Rep. 2018. PMID: 30232010 Free PMC article.
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