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TP53, TP53 Target Genes (DRAM, TIGAR), and Autophagy.
Hu W, Chen S, Thorne RF, Wu M. Hu W, et al. Among authors: chen s. Adv Exp Med Biol. 2019;1206:127-149. doi: 10.1007/978-981-15-0602-4_6. Adv Exp Med Biol. 2019. PMID: 31776983 Review.
Non-coding RNAs, guardians of the p53 galaxy.
Chen S, Thorne RF, Zhang XD, Wu M, Liu L. Chen S, et al. Semin Cancer Biol. 2021 Oct;75:72-83. doi: 10.1016/j.semcancer.2020.09.002. Epub 2020 Sep 11. Semin Cancer Biol. 2021. PMID: 32927018 Review.
KDM6A promotes imatinib resistance through YY1-mediated transcriptional upregulation of TRKA independently of its demethylase activity in chronic myelogenous leukemia.
Zhang C, Shen L, Zhu Y, Xu R, Deng Z, Liu X, Ding Y, Wang C, Shi Y, Bei L, Wei D, Thorne RF, Zhang XD, Yu L, Chen S. Zhang C, et al. Among authors: chen s. Theranostics. 2021 Jan 1;11(6):2691-2705. doi: 10.7150/thno.50571. eCollection 2021. Theranostics. 2021. PMID: 33456567 Free PMC article.
Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells.
La T, Chen S, Guo T, Zhao XH, Teng L, Li D, Carnell M, Zhang YY, Feng YC, Cole N, Brown AC, Zhang D, Dong Q, Wang JY, Cao H, Liu T, Thorne RF, Shao FM, Zhang XD, Jin L. La T, et al. Among authors: chen s. Theranostics. 2021 Sep 21;11(19):9605-9622. doi: 10.7150/thno.63763. eCollection 2021. Theranostics. 2021. PMID: 34646389 Free PMC article.
TRIMming down autophagy in breast cancer.
Thorne RF, Yang Y, Wu M, Chen S. Thorne RF, et al. Among authors: chen s. Autophagy. 2022 Oct;18(10):2512-2513. doi: 10.1080/15548627.2022.2105557. Epub 2022 Jul 27. Autophagy. 2022. PMID: 35897149 Free PMC article.
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