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Combined HIV-1 sequence and integration site analysis informs viral dynamics and allows reconstruction of replicating viral ancestors.
Patro SC, Brandt LD, Bale MJ, Halvas EK, Joseph KW, Shao W, Wu X, Guo S, Murrell B, Wiegand A, Spindler J, Raley C, Hautman C, Sobolewski M, Fennessey CM, Hu WS, Luke B, Hasson JM, Niyongabo A, Capoferri AA, Keele BF, Milush J, Hoh R, Deeks SG, Maldarelli F, Hughes SH, Coffin JM, Rausch JW, Mellors JW, Kearney MF. Patro SC, et al. Among authors: rausch jw. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25891-25899. doi: 10.1073/pnas.1910334116. Epub 2019 Nov 27. Proc Natl Acad Sci U S A. 2019. PMID: 31776247 Free PMC article.
HIV-1 viremia not suppressible by antiretroviral therapy can originate from large T cell clones producing infectious virus.
Halvas EK, Joseph KW, Brandt LD, Guo S, Sobolewski MD, Jacobs JL, Tumiotto C, Bui JK, Cyktor JC, Keele BF, Morse GD, Bale MJ, Shao W, Kearney MF, Coffin JM, Rausch JW, Wu X, Hughes SH, Mellors JW. Halvas EK, et al. Among authors: rausch jw. J Clin Invest. 2020 Nov 2;130(11):5847-5857. doi: 10.1172/JCI138099. J Clin Invest. 2020. PMID: 33016926 Free PMC article.
CpG Methylation Profiles of HIV-1 Pro-Viral DNA in Individuals on ART.
Boltz VF, Ceriani C, Rausch JW, Shao W, Bale MJ, Keele BF, Hoh R, Milush JM, Deeks SG, Maldarelli F, Kearney MF, Coffin JM. Boltz VF, et al. Among authors: rausch jw. Viruses. 2021 Apr 29;13(5):799. doi: 10.3390/v13050799. Viruses. 2021. PMID: 33946976 Free PMC article.
Low genetic diversity may be an Achilles heel of SARS-CoV-2.
Rausch JW, Capoferri AA, Katusiime MG, Patro SC, Kearney MF. Rausch JW, et al. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24614-24616. doi: 10.1073/pnas.2017726117. Epub 2020 Sep 21. Proc Natl Acad Sci U S A. 2020. PMID: 32958678 Free PMC article. No abstract available.
HIV Genetic Diversity - Superpower of a Formidable Virus.
Sherpa C, Rausch JW, Le Grice SFJ. Sherpa C, et al. Among authors: rausch jw. Curr HIV Res. 2020;18(2):69-73. doi: 10.2174/1570162X1802200311104204. Curr HIV Res. 2020. PMID: 32223727 No abstract available.
56 results