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Citraconate inhibits ACOD1 (IRG1) catalysis, reduces interferon responses and oxidative stress, and modulates inflammation and cell metabolism.
Nat Metab. 2022 May;4(5):534-546. doi: 10.1038/s42255-022-00577-x. Epub 2022 Jun 2.
Nat Metab. 2022.
PMID: 35655026
Free PMC article.
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