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Nonhuman primate models for evaluation of SARS-CoV-2 vaccines.
Neil JA, Griffith M, Godfrey DI, Purcell DFJ, Deliyannis G, Jackson D, Rockman S, Subbarao K, Nolan T. Neil JA, et al. Among authors: purcell dfj. Expert Rev Vaccines. 2022 Aug;21(8):1055-1070. doi: 10.1080/14760584.2022.2071264. Epub 2022 Jun 2. Expert Rev Vaccines. 2022. PMID: 35652289
Influenza, but not SARS-CoV-2, infection induces a rapid interferon response that wanes with age and diminished tissue-resident memory CD8+ T cells.
Nguyen TH, McAuley JL, Kim Y, Zheng MZ, Gherardin NA, Godfrey DI, Purcell DF, Sullivan LC, Westall GP, Reading PC, Kedzierska K, Wakim LM. Nguyen TH, et al. Clin Transl Immunology. 2021 Jan 26;10(1):e1242. doi: 10.1002/cti2.1242. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33532071 Free PMC article.
Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial.
Chappell KJ, Mordant FL, Li Z, Wijesundara DK, Ellenberg P, Lackenby JA, Cheung STM, Modhiran N, Avumegah MS, Henderson CL, Hoger K, Griffin P, Bennet J, Hensen L, Zhang W, Nguyen THO, Marrero-Hernandez S, Selva KJ, Chung AW, Tran MH, Tapley P, Barnes J, Reading PC, Nicholson S, Corby S, Holgate T, Wines BD, Hogarth PM, Kedzierska K, Purcell DFJ, Ranasinghe C, Subbarao K, Watterson D, Young PR, Munro TP. Chappell KJ, et al. Among authors: purcell dfj. Lancet Infect Dis. 2021 Oct;21(10):1383-1394. doi: 10.1016/S1473-3099(21)00200-0. Epub 2021 Apr 19. Lancet Infect Dis. 2021. PMID: 33887208 Free PMC article. Clinical Trial.
Nanobody cocktails potently neutralize SARS-CoV-2 D614G N501Y variant and protect mice.
Pymm P, Adair A, Chan LJ, Cooney JP, Mordant FL, Allison CC, Lopez E, Haycroft ER, O'Neill MT, Tan LL, Dietrich MH, Drew D, Doerflinger M, Dengler MA, Scott NE, Wheatley AK, Gherardin NA, Venugopal H, Cromer D, Davenport MP, Pickering R, Godfrey DI, Purcell DFJ, Kent SJ, Chung AW, Subbarao K, Pellegrini M, Glukhova A, Tham WH. Pymm P, et al. Among authors: purcell dfj. Proc Natl Acad Sci U S A. 2021 May 11;118(19):e2101918118. doi: 10.1073/pnas.2101918118. Proc Natl Acad Sci U S A. 2021. PMID: 33893175 Free PMC article.
Transcriptional and epi-transcriptional dynamics of SARS-CoV-2 during cellular infection.
Chang JJ, Rawlinson D, Pitt ME, Taiaroa G, Gleeson J, Zhou C, Mordant FL, De Paoli-Iseppi R, Caly L, Purcell DFJ, Stinear TP, Londrigan SL, Clark MB, Williamson DA, Subbarao K, Coin LJM. Chang JJ, et al. Among authors: purcell dfj. Cell Rep. 2021 May 11;35(6):109108. doi: 10.1016/j.celrep.2021.109108. Epub 2021 Apr 23. Cell Rep. 2021. PMID: 33961822 Free PMC article.
Infrared Based Saliva Screening Test for COVID-19.
Wood BR, Kochan K, Bedolla DE, Salazar-Quiroz N, Grimley SL, Perez-Guaita D, Baker MJ, Vongsvivut J, Tobin MJ, Bambery KR, Christensen D, Pasricha S, Eden AK, Mclean A, Roy S, Roberts JA, Druce J, Williamson DA, McAuley J, Catton M, Purcell DFJ, Godfrey DI, Heraud P. Wood BR, et al. Among authors: purcell dfj. Angew Chem Int Ed Engl. 2021 Jul 26;60(31):17102-17107. doi: 10.1002/anie.202104453. Epub 2021 Jun 29. Angew Chem Int Ed Engl. 2021. PMID: 34043272 Free PMC article.
Simultaneous evaluation of antibodies that inhibit SARS-CoV-2 variants via multiplex assay.
Lopez E, Haycroft ER, Adair A, Mordant FL, O'Neill MT, Pymm P, Redmond SJ, Lee WS, Gherardin NA, Wheatley AK, Juno JA, Selva KJ, Davis SK, Grimley SL, Harty L, Purcell DF, Subbarao K, Godfrey DI, Kent SJ, Tham WH, Chung AW. Lopez E, et al. JCI Insight. 2021 Aug 23;6(16):e150012. doi: 10.1172/jci.insight.150012. JCI Insight. 2021. PMID: 34251356 Free PMC article.
156 results