Sigalapalli DK - Search Results

1

Design, synthesis of DNA-interactive 4-thiazolidinone-based indolo-/pyrroloazepinone conjugates as potential cytotoxic and topoisomerase I inhibitors.

Kadagathur M, Patra S, Devabattula G, George J, Phanindranath R, Shaikh AS, Sigalapalli DK, Godugu C, Nagesh N, Tangellamudi ND, Shankaraiah N. Kadagathur M, et al. Among authors: sigalapalli dk. Eur J Med Chem. 2022 Aug 5;238:114465. doi: 10.1016/j.ejmech.2022.114465. Epub 2022 May 18. Eur J Med Chem. 2022. PMID: 35635947

2

Synthesis and α-glucosidase inhibition activity of dihydroxy pyrrolidines.

Kasturi S, Surarapu S, Uppalanchi S, Anireddy JS, Dwivedi S, Anantaraju HS, Perumal Y, Sigalapalli DK, Babu BN, Ethiraj KS. Kasturi S, et al. Among authors: sigalapalli dk. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2818-2823. doi: 10.1016/j.bmcl.2017.04.078. Epub 2017 May 2. Bioorg Med Chem Lett. 2017. PMID: 28495082

3

Synthesis of thiazole linked indolyl-3-glyoxylamide derivatives as tubulin polymerization inhibitors.

Guggilapu SD, Guntuku L, Reddy TS, Nagarsenkar A, Sigalapalli DK, Naidu VGM, Bhargava SK, Bathini NB. Guggilapu SD, et al. Among authors: sigalapalli dk. Eur J Med Chem. 2017 Sep 29;138:83-95. doi: 10.1016/j.ejmech.2017.06.025. Epub 2017 Jun 15. Eur J Med Chem. 2017. PMID: 28648953

4

Synthesis and biological evaluation of curcumin inspired imidazo[1,2-a]pyridine analogues as tubulin polymerization inhibitors.

Ramya PVS, Guntuku L, Angapelly S, Digwal CS, Lakshmi UJ, Sigalapalli DK, Babu BN, Naidu VGM, Kamal A. Ramya PVS, et al. Among authors: sigalapalli dk. Eur J Med Chem. 2018 Jan 1;143:216-231. doi: 10.1016/j.ejmech.2017.11.010. Epub 2017 Nov 5. Eur J Med Chem. 2018. PMID: 29174816

5

Synthesis, molecular modeling and evaluation of α-glucosidase inhibition activity of 3,4-dihydroxy piperidines.

Kasturi SP, Surarapu S, Uppalanchi S, Dwivedi S, Yogeeswari P, Sigalapalli DK, Bathini NB, Ethiraj KS, Anireddy JS. Kasturi SP, et al. Among authors: sigalapalli dk. Eur J Med Chem. 2018 Apr 25;150:39-52. doi: 10.1016/j.ejmech.2018.02.072. Epub 2018 Feb 26. Eur J Med Chem. 2018. PMID: 29518717

6

Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation.

Pooladanda V, Thatikonda S, Bale S, Pattnaik B, Sigalapalli DK, Bathini NB, Singh SB, Godugu C. Pooladanda V, et al. Among authors: sigalapalli dk. Cell Death Dis. 2019 Jan 28;10(2):81. doi: 10.1038/s41419-018-1247-9. Cell Death Dis. 2019. PMID: 30692512 Free PMC article.

7

Discovery of certain benzyl/phenethyl thiazolidinone-indole hybrids as potential anti-proliferative agents: Synthesis, molecular modeling and tubulin polymerization inhibition study.

Sigalapalli DK, Pooladanda V, Singh P, Kadagathur M, Guggilapu SD, Uppu JL, Tangellamudi ND, Gangireddy PK, Godugu C, Bathini NB. Sigalapalli DK, et al. Bioorg Chem. 2019 Nov;92:103188. doi: 10.1016/j.bioorg.2019.103188. Epub 2019 Aug 10. Bioorg Chem. 2019. PMID: 31450167

8

Piperlongumine regulates epigenetic modulation and alleviates psoriasis-like skin inflammation via inhibition of hyperproliferation and inflammation.

Thatikonda S, Pooladanda V, Sigalapalli DK, Godugu C. Thatikonda S, et al. Among authors: sigalapalli dk. Cell Death Dis. 2020 Jan 10;11(1):21. doi: 10.1038/s41419-019-2212-y. Cell Death Dis. 2020. PMID: 31924750 Free PMC article.

9

Novel diindoloazepinone derivatives as DNA minor groove binding agents with selective topoisomerase I inhibition: Design, synthesis, biological evaluation and docking studies.

Kadagathur M, Devi GP, Grewal P, Sigalapalli DK, Makhal PN, Banerjee UC, Bathini NB, Tangellamudi ND. Kadagathur M, et al. Among authors: sigalapalli dk. Bioorg Chem. 2020 Jun;99:103629. doi: 10.1016/j.bioorg.2020.103629. Epub 2020 Jan 28. Bioorg Chem. 2020. PMID: 32272367

10

Design and synthesis of β-carboline linked aryl sulfonyl piperazine derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing ability.

Lakshmi Manasa K, Thatikonda S, Sigalapalli DK, Sagar A, Kiranmai G, Kalle AM, Alvala M, Godugu C, Nagesh N, Nagendra Babu B. Lakshmi Manasa K, et al. Among authors: sigalapalli dk. Bioorg Chem. 2020 Aug;101:103983. doi: 10.1016/j.bioorg.2020.103983. Epub 2020 Jun 1. Bioorg Chem. 2020. PMID: 32683136

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