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Alkyl Derivatives of Perylene Photosensitizing Antivirals: Towards Understanding the Influence of Lipophilicity.
Mikhnovets IE, Holoubek J, Panina IS, Kotouček J, Gvozdev DA, Chumakov SP, Krasilnikov MS, Zhitlov MY, Gulyak EL, Chistov AA, Nikitin TD, Korshun VA, Efremov RG, Alferova VA, Růžek D, Eyer L, Ustinov AV. Mikhnovets IE, et al. Among authors: nikitin td. Int J Mol Sci. 2023 Nov 18;24(22):16483. doi: 10.3390/ijms242216483. Int J Mol Sci. 2023. PMID: 38003673 Free PMC article.
Membrane-Targeting Perylenylethynylphenols Inactivate Medically Important Coronaviruses via the Singlet Oxygen Photogeneration Mechanism.
Mariewskaya KA, Gvozdev DA, Chistov AA, Straková P, Huvarová I, Svoboda P, Kotouček J, Ivanov NM, Krasilnikov MS, Zhitlov MY, Pak AM, Mikhnovets IE, Nikitin TD, Korshun VA, Alferova VA, Mašek J, Růžek D, Eyer L, Ustinov AV. Mariewskaya KA, et al. Among authors: nikitin td. Molecules. 2023 Aug 28;28(17):6278. doi: 10.3390/molecules28176278. Molecules. 2023. PMID: 37687107 Free PMC article.
Antiviral activity of singlet oxygen-photogenerating perylene compounds against SARS-CoV-2: Interaction with the viral envelope and photodynamic virion inactivation.
Straková P, Bednář P, Kotouček J, Holoubek J, Fořtová A, Svoboda P, Štefánik M, Huvarová I, Šimečková P, Mašek J, Gvozdev DA, Mikhnovets IE, Chistov AA, Nikitin TD, Krasilnikov MS, Ustinov AV, Alferova VA, Korshun VA, Růžek D, Eyer L. Straková P, et al. Among authors: nikitin td. Virus Res. 2023 Sep;334:199158. doi: 10.1016/j.virusres.2023.199158. Epub 2023 Jun 29. Virus Res. 2023. PMID: 37339718 Free PMC article.
5-(Perylen-3-ylethynyl)uracil as an antiviral scaffold: Potent suppression of enveloped virus reproduction by 3-methyl derivatives in vitro.
Chistov AA, Chumakov SP, Mikhnovets IE, Nikitin TD, Slesarchuk NA, Uvarova VI, Rubekina AA, Nikolaeva YV, Radchenko EV, Khvatov EV, Orlov AA, Frolenko VS, Sukhorukov MV, Kolpakova ES, Shustova EY, Galochkina AV, Streshnev PP, Osipov EM, Sapozhnikova KA, Moiseenko AV, Brylev VA, Proskurin GV, Dokukin YS, Kutyakov SV, Aralov AV, Korshun VA, Strelkov SV, Palyulin VA, Ishmukhametov AA, Shirshin EA, Osolodkin DI, Shtro AA, Kozlovskaya LI, Alferova VA, Ustinov AV. Chistov AA, et al. Among authors: nikitin td. Antiviral Res. 2023 Jan;209:105508. doi: 10.1016/j.antiviral.2022.105508. Epub 2022 Dec 26. Antiviral Res. 2023. PMID: 36581049
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