Manley P - Search Results

1

In Vivo Evaluation of Fibroblast Growth Factor Receptor Inhibition in Mouse Xenograft Models of Gastrointestinal Stromal Tumor.

Schöffski P, Gebreyohannes Y, Van Looy T, Manley P, Growney JD, Squires M, Wozniak A. Schöffski P, et al. Among authors: manley p. Biomedicines. 2022 May 13;10(5):1135. doi: 10.3390/biomedicines10051135. Biomedicines. 2022. PMID: 35625872 Free PMC article.

2

Phosphoinositide 3-kinase inhibitors combined with imatinib in patient-derived xenograft models of gastrointestinal stromal tumors: rationale and efficacy.

Van Looy T, Wozniak A, Floris G, Sciot R, Li H, Wellens J, Vanleeuw U, Fletcher JA, Manley PW, Debiec-Rychter M, Schöffski P. Van Looy T, et al. Among authors: manley pw. Clin Cancer Res. 2014 Dec 1;20(23):6071-82. doi: 10.1158/1078-0432.CCR-14-1823. Epub 2014 Oct 14. Clin Cancer Res. 2014. PMID: 25316817

3

Cellular uptake of the tyrosine kinase inhibitors imatinib and AMN107 in gastrointestinal stromal tumor cell lines.

Prenen H, Guetens G, de Boeck G, Debiec-Rychter M, Manley P, Schoffski P, van Oosterom AT, de Bruijn E. Prenen H, et al. Among authors: manley p. Pharmacology. 2006;77(1):11-6. doi: 10.1159/000091943. Epub 2006 Mar 8. Pharmacology. 2006. PMID: 16534250

4

Therapies directed at vascular endothelial growth factor.

Manley PW, Martiny-Baron G, Schlaeppi JM, Wood JM. Manley PW, et al. Expert Opin Investig Drugs. 2002 Dec;11(12):1715-36. doi: 10.1517/13543784.11.12.1715. Expert Opin Investig Drugs. 2002. PMID: 12457433 Review.

5

A Novel Potent Oral Series of VEGFR2 Inhibitors Abrogate Tumor Growth by Inhibiting Angiogenesis.

Bold G, Schnell C, Furet P, McSheehy P, Brüggen J, Mestan J, Manley PW, Drückes P, Burglin M, Dürler U, Loretan J, Reuter R, Wartmann M, Theuer A, Bauer-Probst B, Martiny-Baron G, Allegrini P, Goepfert A, Wood J, Littlewood-Evans A. Bold G, et al. Among authors: manley pw. J Med Chem. 2016 Jan 14;59(1):132-46. doi: 10.1021/acs.jmedchem.5b01582. Epub 2015 Dec 21. J Med Chem. 2016. PMID: 26629594

6

Midostaurin: its odyssey from discovery to approval for treating acute myeloid leukemia and advanced systemic mastocytosis.

Stone RM, Manley PW, Larson RA, Capdeville R. Stone RM, et al. Blood Adv. 2018 Feb 27;2(4):444-453. doi: 10.1182/bloodadvances.2017011080. Blood Adv. 2018. PMID: 29487059 Free PMC article. Review.

7

Spotlight on midostaurin in the treatment of FLT3-mutated acute myeloid leukemia and systemic mastocytosis: design, development, and potential place in therapy.

Weisberg E, Sattler M, Manley PW, Griffin JD. Weisberg E, et al. Onco Targets Ther. 2017 Dec 29;11:175-182. doi: 10.2147/OTT.S127679. eCollection 2018. Onco Targets Ther. 2017. PMID: 29343975 Free PMC article. Review.

8

Inhibition of SDF-1-induced migration of oncogene-driven myeloid leukemia by the L-RNA aptamer (Spiegelmer), NOX-A12, and potentiation of tyrosine kinase inhibition.

Weisberg EL, Sattler M, Azab AK, Eulberg D, Kruschinski A, Manley PW, Stone R, Griffin JD. Weisberg EL, et al. Oncotarget. 2017 Nov 6;8(66):109973-109984. doi: 10.18632/oncotarget.22409. eCollection 2017 Dec 15. Oncotarget. 2017. PMID: 29299123 Free PMC article.

9

Anthranilic acid amides: a novel class of antiangiogenic VEGF receptor kinase inhibitors.

Manley PW, Furet P, Bold G, Brüggen J, Mestan J, Meyer T, Schnell CR, Wood J, Haberey M, Huth A, Krüger M, Menrad A, Ottow E, Seidelmann D, Siemeister G, Thierauch KH. Manley PW, et al. J Med Chem. 2002 Dec 19;45(26):5687-93. doi: 10.1021/jm020899q. J Med Chem. 2002. PMID: 12477352

10

Imatinib relaxes the pulmonary venous bed of guinea pigs.

Maihöfer NA, Suleiman S, Dreymüller D, Manley PW, Rossaint R, Uhlig S, Martin C, Rieg AD. Maihöfer NA, et al. Respir Res. 2017 Feb 8;18(1):32. doi: 10.1186/s12931-017-0514-0. Respir Res. 2017. PMID: 28178968 Free PMC article.

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