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Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction.
Kefala Stavridi A, Gontier A, Morin V, Frit P, Ropars V, Barboule N, Racca C, Jonchhe S, Morten MJ, Andreani J, Rak A, Legrand P, Bourand-Plantefol A, Hardwick SW, Chirgadze DY, Davey P, De Oliveira TM, Rothenberg E, Britton S, Calsou P, Blundell TL, Varela PF, Chaplin AK, Charbonnier JB. Kefala Stavridi A, et al. Among authors: gontier a. Nucleic Acids Res. 2023 Nov 27;51(21):11732-11747. doi: 10.1093/nar/gkad863. Nucleic Acids Res. 2023. PMID: 37870477 Free PMC article.
Clickable Bambusurils to Access Multivalent Architectures.
Lafosse M, Cartier E, Solmont K, Rivollier J, Azazna D, Thuéry P, Boulard Y, Gontier A, Charbonnier JB, Kuhnast B, Heck MP. Lafosse M, et al. Among authors: gontier a. Org Lett. 2020 Apr 17;22(8):3099-3103. doi: 10.1021/acs.orglett.0c00856. Epub 2020 Apr 3. Org Lett. 2020. PMID: 32243185
XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nemoz C, Ropars V, Frit P, Gontier A, Drevet P, Yu J, Guerois R, Pitois A, Comte A, Delteil C, Barboule N, Legrand P, Baconnais S, Yin Y, Tadi S, Barbet-Massin E, Berger I, Le Cam E, Modesti M, Rothenberg E, Calsou P, Charbonnier JB. Nemoz C, et al. Among authors: gontier a. Nat Struct Mol Biol. 2018 Oct;25(10):971-980. doi: 10.1038/s41594-018-0133-6. Epub 2018 Oct 5. Nat Struct Mol Biol. 2018. PMID: 30291363 Free PMC article.
In vitro activity of cefiderocol against European Pseudomonas aeruginosa and Acinetobacter spp., including isolates resistant to meropenem and recent β-lactam/β-lactamase inhibitor combinations.
Santerre Henriksen A, Jeannot K, Oliver A, Perry JD, Pletz MW, Stefani S, Morrissey I, Longshaw C; ARTEMIS Study Investigators. Santerre Henriksen A, et al. Microbiol Spectr. 2024 Apr 2;12(4):e0383623. doi: 10.1128/spectrum.03836-23. Epub 2024 Mar 14. Microbiol Spectr. 2024. PMID: 38483164 Free PMC article.
15 results