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Relationship between Anti-Spike Protein Antibody Titers and SARS-CoV-2 In Vitro Virus Neutralization in Convalescent Plasma.
Salazar E, Kuchipudi SV, Christensen PA, Eagar TN, Yi X, Zhao P, Jin Z, Long SW, Olsen RJ, Chen J, Castillo B, Leveque C, Towers DM, Lavinder J, Gollihar JD, Cardona J, Ippolito GC, Nissly RH, Bird IM, Greenawalt D, Rossi RM, Gontu A, Srinivasan S, Poojary IB, Cattadori IM, Hudson PJ, Joselyn N, Prugar L, Huie K, Herbert A, Bernard DW, Dye J, Kapur V, Musser JM. Salazar E, et al. Among authors: kuchipudi sv. bioRxiv [Preprint]. 2020 Jun 9:2020.06.08.138990. doi: 10.1101/2020.06.08.138990. bioRxiv. 2020. PMID: 32577662 Free PMC article. Updated. Preprint.
Convalescent plasma anti-SARS-CoV-2 spike protein ectodomain and receptor-binding domain IgG correlate with virus neutralization.
Salazar E, Kuchipudi SV, Christensen PA, Eagar T, Yi X, Zhao P, Jin Z, Long SW, Olsen RJ, Chen J, Castillo B, Leveque C, Towers D, Lavinder J, Gollihar J, Cardona J, Ippolito G, Nissly R, Bird I, Greenawalt D, Rossi RM, Gontu A, Srinivasan S, Poojary I, Cattadori IM, Hudson PJ, Josleyn NM, Prugar L, Huie K, Herbert A, Bernard DW, Dye JM, Kapur V, Musser JM. Salazar E, et al. Among authors: kuchipudi sv. J Clin Invest. 2020 Dec 1;130(12):6728-6738. doi: 10.1172/JCI141206. J Clin Invest. 2020. PMID: 32910806 Free PMC article. Clinical Trial.
Limited window for donation of convalescent plasma with high live-virus neutralizing antibody titers for COVID-19 immunotherapy.
Gontu A, Srinivasan S, Salazar E, Nair MS, Nissly RH, Greenawalt D, Bird IM, Herzog CM, Ferrari MJ, Poojary I, Katani R, Lindner SE, Minns AM, Rossi R, Christensen PA, Castillo B, Chen J, Eagar TN, Yi X, Zhao P, Leveque C, Olsen RJ, Bernard DW, Gollihar J, Kuchipudi SV, Musser JM, Kapur V. Gontu A, et al. Among authors: kuchipudi sv. Commun Biol. 2021 Feb 24;4(1):267. doi: 10.1038/s42003-021-01813-y. Commun Biol. 2021. PMID: 33627795 Free PMC article.
Neutralizing Aptamers Block S/RBD-ACE2 Interactions and Prevent Host Cell Infection.
Liu X, Wang YL, Wu J, Qi J, Zeng Z, Wan Q, Chen Z, Manandhar P, Cavener VS, Boyle NR, Fu X, Salazar E, Kuchipudi SV, Kapur V, Zhang X, Umetani M, Sen M, Willson RC, Chen SH, Zu Y. Liu X, et al. Among authors: kuchipudi sv. Angew Chem Int Ed Engl. 2021 Apr 26;60(18):10273-10278. doi: 10.1002/anie.202100345. Epub 2021 Mar 22. Angew Chem Int Ed Engl. 2021. PMID: 33684258 Free PMC article.
Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality.
Goike J, Hsieh CL, Horton A, Gardner EC, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Renberg R, Johanson MJ, Cardona JA, Segall-Shapiro T, Zhou L, Nissly RH, Gontu A, Byrom M, Maranhao AC, Battenhouse AM, Gejji V, Soto-Sierra L, Foster ER, Woodard SL, Nikolov ZL, Lavinder J, Voss WN, Annapareddy A, Ippolito GC, Ellington AD, Marcotte EM, Finkelstein IJ, Hughes RA, Musser JM, Kuchipudi SV, Kapur V, Georgiou G, Dye JM, Boutz DR, McLellan JS, Gollihar JD. Goike J, et al. Among authors: kuchipudi sv. bioRxiv [Preprint]. 2021 Apr 9:2021.04.07.438849. doi: 10.1101/2021.04.07.438849. bioRxiv. 2021. PMID: 33851158 Free PMC article. Preprint.
Neutralizing Aptamers Block S/RBD-ACE2 Interactions and Prevent Host Cell Infection.
Liu X, Wang YL, Wu J, Qi J, Zeng Z, Wan Q, Chen Z, Manandhar P, Cavener VS, Boyle NR, Fu X, Salazar E, Kuchipudi SV, Kapur V, Zhang X, Umetani M, Sen M, Willson RC, Chen SH, Zu Y. Liu X, et al. Among authors: kuchipudi sv. Angew Chem Weinheim Bergstr Ger. 2021 Apr 26;133(18):10361-10366. doi: 10.1002/ange.202100345. Epub 2021 Mar 22. Angew Chem Weinheim Bergstr Ger. 2021. PMID: 34230707 Free PMC article.
Computational prediction of the effect of amino acid changes on the binding affinity between SARS-CoV-2 spike RBD and human ACE2.
Chen C, Boorla VS, Banerjee D, Chowdhury R, Cavener VS, Nissly RH, Gontu A, Boyle NR, Vandegrift K, Nair MS, Kuchipudi SV, Maranas CD. Chen C, et al. Among authors: kuchipudi sv. Proc Natl Acad Sci U S A. 2021 Oct 19;118(42):e2106480118. doi: 10.1073/pnas.2106480118. Proc Natl Acad Sci U S A. 2021. PMID: 34588290 Free PMC article.
Monoclonal Antibodies to S and N SARS-CoV-2 Proteins as Probes to Assess Structural and Antigenic Properties of Coronaviruses.
Kumar R, Christensen ND, Kaddis Maldonado RJ, Bewley MC, Ostman A, Sudol M, Chen EC, Buchkovich NW, Gontu A, Surendran Nair M, Nissly RH, Minns AM, Kapur V, Rossi R, Kuchipudi SV, Lindner SE, Parent LJ, Flanagan JM, Buchkovich NJ. Kumar R, et al. Among authors: kuchipudi sv. Viruses. 2021 Sep 22;13(10):1899. doi: 10.3390/v13101899. Viruses. 2021. PMID: 34696329 Free PMC article.
83 results