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Acute toxicity and antitumor potential of 1,3,4-trisubstituted-1,2,3-triazole dhmtAc-loaded liposomes on a triple-negative breast cancer model.
Ramos JP, Abdel-Salam MAL, Nobre DAB, Glanzmann N, de Souza CP, Leite EA, de Abreu Teles PP, Barbosa AS, Barcelos LS, Dos Reis DC, Cassali GD, de Lima ME, de Castro QJT, Grabe-Guimarães A, da Silva AD, de Souza-Fagundes EM. Ramos JP, et al. Among authors: de lima me. Arch Pharm (Weinheim). 2022 Sep;355(9):e2200004. doi: 10.1002/ardp.202200004. Epub 2022 May 27. Arch Pharm (Weinheim). 2022. PMID: 35621705
The synthetic peptide LyeTxI-b derived from Lycosa erythrognatha spider venom is cytotoxic to U-87 MG glioblastoma cells.
Abdel-Salam MAL, Carvalho-Tavares J, Gomes KS, Teixeira-Carvalho A, Kitten GT, Nyffeler J, Dias FF, Dos Reis PVM, Pimenta AMC, Leist M, de Lima ME, de Souza-Fagundes EM. Abdel-Salam MAL, et al. Among authors: de souza fagundes em, de lima me. Amino Acids. 2019 Mar;51(3):433-449. doi: 10.1007/s00726-018-2678-4. Epub 2018 Nov 17. Amino Acids. 2019. PMID: 30449002
Shortened derivatives from native antimicrobial peptide LyeTx I: In vitro and in vivo biological activity assessment.
Fuscaldi LL, de Avelar Júnior JT, Dos Santos DM, Boff D, de Oliveira VLS, Gomes KAGG, Cruz RC, de Oliveira PL, Magalhães PP, Cisalpino PS, Farias LM, de Souza-Fagundes EM, Delp J, Leist M, Resende JM, Amaral FA, Pimenta AMC, Fernandes SOA, Cardoso VN, de Lima ME. Fuscaldi LL, et al. Among authors: de oliveira vls, de souza fagundes em, de lima me, de avelar junior jt, de oliveira pl. Exp Biol Med (Maywood). 2021 Feb;246(4):414-425. doi: 10.1177/1535370220966963. Epub 2020 Nov 11. Exp Biol Med (Maywood). 2021. PMID: 33175610 Free PMC article.
LyeTxI-b, a Synthetic Peptide Derived From a Spider Venom, Is Highly Active in Triple-Negative Breast Cancer Cells and Acts Synergistically With Cisplatin.
de Avelar Júnior JT, Lima-Batista E, Castro Junior CJ, Pimenta AMC, Dos Santos RG, Souza-Fagundes EM, De Lima ME. de Avelar Júnior JT, et al. Among authors: de lima me. Front Mol Biosci. 2022 May 4;9:876833. doi: 10.3389/fmolb.2022.876833. eCollection 2022. Front Mol Biosci. 2022. PMID: 35601827 Free PMC article.
Physicochemical Characterization and Skin Permeation of Cationic Transfersomes Containing the Synthetic Peptide PnPP-19.
De Marco Almeida F, Silva CN, de Araujo Lopes SC, Santos DM, Torres FS, Cardoso FL, Martinelli PM, da Silva ER, de Lima ME, Miranda LAF, Oliveira MC. De Marco Almeida F, et al. Among authors: de lima me, de araujo lopes sc. Curr Drug Deliv. 2018;15(7):1064-1071. doi: 10.2174/1567201815666180108170206. Curr Drug Deliv. 2018. PMID: 29318970
The synthetic peptide PnPP-19 potentiates erectile function via nNOS and iNOS.
Silva CND, Pedrosa KN, Silva GCD, Cunha PDS, Diniz TF, Maia LMS, Almeida FM, Gomez RS, Lemos VS, Gomes DA, de Lima ME. Silva CND, et al. Among authors: de lima me. Nitric Oxide. 2021 Sep 1;113-114:23-30. doi: 10.1016/j.niox.2021.04.007. Epub 2021 Apr 26. Nitric Oxide. 2021. PMID: 33915274
137 results