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Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes.
Bushell E, Gomes AR, Sanderson T, Anar B, Girling G, Herd C, Metcalf T, Modrzynska K, Schwach F, Martin RE, Mather MW, McFadden GI, Parts L, Rutledge GG, Vaidya AB, Wengelnik K, Rayner JC, Billker O. Bushell E, et al. Cell. 2017 Jul 13;170(2):260-272.e8. doi: 10.1016/j.cell.2017.06.030. Cell. 2017. PMID: 28708996 Free PMC article.
Genome-Scale Identification of Essential Metabolic Processes for Targeting the Plasmodium Liver Stage.
Stanway RR, Bushell E, Chiappino-Pepe A, Roques M, Sanderson T, Franke-Fayard B, Caldelari R, Golomingi M, Nyonda M, Pandey V, Schwach F, Chevalley S, Ramesar J, Metcalf T, Herd C, Burda PC, Rayner JC, Soldati-Favre D, Janse CJ, Hatzimanikatis V, Billker O, Heussler VT. Stanway RR, et al. Cell. 2019 Nov 14;179(5):1112-1128.e26. doi: 10.1016/j.cell.2019.10.030. Cell. 2019. PMID: 31730853 Free PMC article.
Regulators of male and female sexual development are critical for the transmission of a malaria parasite.
Russell AJC, Sanderson T, Bushell E, Talman AM, Anar B, Girling G, Hunziker M, Kent RS, Martin JS, Metcalf T, Montandon R, Pandey V, Pardo M, Roberts AB, Sayers C, Schwach F, Choudhary JS, Rayner JC, Voet T, Modrzynska KK, Waters AP, Lawniczak MKN, Billker O. Russell AJC, et al. Cell Host Microbe. 2023 Feb 8;31(2):305-319.e10. doi: 10.1016/j.chom.2022.12.011. Epub 2023 Jan 11. Cell Host Microbe. 2023. PMID: 36634679 Free article.
Comparative genomics in Chlamydomonas and Plasmodium identifies an ancient nuclear envelope protein family essential for sexual reproduction in protists, fungi, plants, and vertebrates.
Ning J, Otto TD, Pfander C, Schwach F, Brochet M, Bushell E, Goulding D, Sanders M, Lefebvre PA, Pei J, Grishin NV, Vanderlaan G, Billker O, Snell WJ. Ning J, et al. Genes Dev. 2013 May 15;27(10):1198-215. doi: 10.1101/gad.212746.112. Genes Dev. 2013. PMID: 23699412 Free PMC article.
A cascade of DNA-binding proteins for sexual commitment and development in Plasmodium.
Sinha A, Hughes KR, Modrzynska KK, Otto TD, Pfander C, Dickens NJ, Religa AA, Bushell E, Graham AL, Cameron R, Kafsack BFC, Williams AE, Llinas M, Berriman M, Billker O, Waters AP. Sinha A, et al. Nature. 2014 Mar 13;507(7491):253-257. doi: 10.1038/nature12970. Epub 2014 Feb 23. Nature. 2014. PMID: 24572359 Free PMC article.
18 results