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Targeted disruption of Na+/Ca2+ exchanger 3 (NCX3) gene leads to a worsening of ischemic brain damage.
Molinaro P, Cuomo O, Pignataro G, Boscia F, Sirabella R, Pannaccione A, Secondo A, Scorziello A, Adornetto A, Gala R, Viggiano D, Sokolow S, Herchuelz A, Schurmans S, Di Renzo G, Annunziato L. Molinaro P, et al. Among authors: boscia f. J Neurosci. 2008 Jan 30;28(5):1179-84. doi: 10.1523/JNEUROSCI.4671-07.2008. J Neurosci. 2008. PMID: 18234895 Free PMC article.
Na+ -Ca2+ exchanger (NCX3) knock-out mice display an impairment in hippocampal long-term potentiation and spatial learning and memory.
Molinaro P, Viggiano D, Nisticò R, Sirabella R, Secondo A, Boscia F, Pannaccione A, Scorziello A, Mehdawy B, Sokolow S, Herchuelz A, Di Renzo GF, Annunziato L. Molinaro P, et al. Among authors: boscia f. J Neurosci. 2011 May 18;31(20):7312-21. doi: 10.1523/JNEUROSCI.6296-10.2011. J Neurosci. 2011. PMID: 21593315 Free PMC article.
A new concept: Aβ1-42 generates a hyperfunctional proteolytic NCX3 fragment that delays caspase-12 activation and neuronal death.
Pannaccione A, Secondo A, Molinaro P, D'Avanzo C, Cantile M, Esposito A, Boscia F, Scorziello A, Sirabella R, Sokolow S, Herchuelz A, Di Renzo G, Annunziato L. Pannaccione A, et al. Among authors: boscia f. J Neurosci. 2012 Aug 1;32(31):10609-17. doi: 10.1523/JNEUROSCI.6429-11.2012. J Neurosci. 2012. PMID: 22855810 Free PMC article.
Extracellular signal-related kinase 2/specificity protein 1/specificity protein 3/repressor element-1 silencing transcription factor pathway is involved in Aroclor 1254-induced toxicity in SH-SY5Y neuronal cells.
Formisano L, Guida N, Laudati G, Boscia F, Esposito A, Secondo A, Di Renzo G, Canzoniero LM. Formisano L, et al. Among authors: boscia f. J Neurosci Res. 2015 Jan;93(1):167-77. doi: 10.1002/jnr.23464. Epub 2014 Aug 5. J Neurosci Res. 2015. PMID: 25093670
The Na+/Ca2+ Exchanger 3 Is Functionally Coupled With the NaV1.6 Voltage-Gated Channel and Promotes an Endoplasmic Reticulum Ca2+ Refilling in a Transgenic Model of Alzheimer's Disease.
Piccialli I, Ciccone R, Secondo A, Boscia F, Tedeschi V, de Rosa V, Cepparulo P, Annunziato L, Pannaccione A. Piccialli I, et al. Among authors: boscia f. Front Pharmacol. 2021 Dec 8;12:775271. doi: 10.3389/fphar.2021.775271. eCollection 2021. Front Pharmacol. 2021. PMID: 34955845 Free PMC article.
263 results