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EF-hand protein, EfhP, specifically binds Ca2+ and mediates Ca2+ regulation of virulence in a human pathogen Pseudomonas aeruginosa.
Kayastha BB, Kubo A, Burch-Konda J, Dohmen RL, McCoy JL, Rogers RR, Mares S, Bevere J, Huckaby A, Witt W, Peng S, Chaudhary B, Mohanty S, Barbier M, Cook G, Deng J, Patrauchan MA. Kayastha BB, et al. Among authors: witt w. Sci Rep. 2022 May 25;12(1):8791. doi: 10.1038/s41598-022-12584-9. Sci Rep. 2022. PMID: 35614085 Free PMC article.
Long-Term Analysis of Pertussis Vaccine Immunity to Identify Potential Markers of Vaccine-Induced Memory Associated With Whole Cell But Not Acellular Pertussis Immunization in Mice.
Weaver KL, Blackwood CB, Horspool AM, Pyles GM, Sen-Kilic E, Grayson EM, Huckaby AB, Witt WT, DeJong MA, Wolf MA, Damron FH, Barbier M. Weaver KL, et al. Front Immunol. 2022 Feb 8;13:838504. doi: 10.3389/fimmu.2022.838504. eCollection 2022. Front Immunol. 2022. PMID: 35211125 Free PMC article.
Development of an anti-Pseudomonas aeruginosa therapeutic monoclonal antibody WVDC-5244.
Horspool AM, Sen-Kilic E, Malkowski AC, Breslow SL, Mateu-Borras M, Hudson MS, Nunley MA, Elliott S, Ray K, Snyder GA, Miller SJ, Kang J, Blackwood CB, Weaver KL, Witt WT, Huckaby AB, Pyles GM, Clark T, Al Qatarneh S, Lewis GK, Damron FH, Barbier M. Horspool AM, et al. Among authors: witt wt. Front Cell Infect Microbiol. 2023 Apr 14;13:1117844. doi: 10.3389/fcimb.2023.1117844. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37124031 Free PMC article.
Intranasal challenge with B. pertussis leads to more severe disease manifestations in mice than aerosol challenge.
Weaver KL, Bitzer GJ, Wolf MA, Pyles GM, DeJong MA, Dublin SR, Huckaby AB, Gutierrez MP, Hall JM, Wong TY, Warden M, Petty JE, Witt WT, Cunningham C, Sen-Kilic E, Damron FH, Barbier M. Weaver KL, et al. Among authors: witt wt. PLoS One. 2023 Nov 2;18(11):e0286925. doi: 10.1371/journal.pone.0286925. eCollection 2023. PLoS One. 2023. PMID: 37917623 Free PMC article.
245 results