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Tuberculosis Drug Discovery: Challenges and New Horizons.
Fernandes GFS, Thompson AM, Castagnolo D, Denny WA, Dos Santos JL. Fernandes GFS, et al. Among authors: castagnolo d. J Med Chem. 2022 Jun 9;65(11):7489-7531. doi: 10.1021/acs.jmedchem.2c00227. Epub 2022 May 25. J Med Chem. 2022. PMID: 35612311 Review.
Design and Synthesis of 1-((1,5-Bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine (BM212) and N-Adamantan-2-yl-N'-((E)-3,7-dimethylocta-2,6-dienyl)ethane-1,2-diamine (SQ109) Pyrrole Hybrid Derivatives: Discovery of Potent Antitubercular Agents Effective against Multidrug-Resistant Mycobacteria.
Bhakta S, Scalacci N, Maitra A, Brown AK, Dasugari S, Evangelopoulos D, McHugh TD, Mortazavi PN, Twist A, Petricci E, Manetti F, Castagnolo D. Bhakta S, et al. Among authors: castagnolo d. J Med Chem. 2016 Mar 24;59(6):2780-93. doi: 10.1021/acs.jmedchem.6b00031. Epub 2016 Mar 8. J Med Chem. 2016. PMID: 26907951 Free article.
Antimicrobial drugs bearing guanidine moieties: A review.
Kim SH, Semenya D, Castagnolo D. Kim SH, et al. Among authors: castagnolo d. Eur J Med Chem. 2021 Apr 15;216:113293. doi: 10.1016/j.ejmech.2021.113293. Epub 2021 Feb 13. Eur J Med Chem. 2021. PMID: 33640673 Review.
Structural Rigidification of N-Aryl-pyrroles into Indoles Active against Intracellular and Drug-Resistant Mycobacteria.
Semenya D, Touitou M, Ribeiro CM, Pavan FR, Pisano L, Singh V, Chibale K, Bano G, Toscani A, Manetti F, Gianibbi B, Castagnolo D. Semenya D, et al. Among authors: castagnolo d. ACS Med Chem Lett. 2021 Dec 8;13(1):63-69. doi: 10.1021/acsmedchemlett.1c00431. eCollection 2022 Jan 13. ACS Med Chem Lett. 2021. PMID: 35059125 Free PMC article.
Oxazolidinones as versatile scaffolds in medicinal chemistry.
Fernandes GFS, Scarim CB, Kim SH, Wu J, Castagnolo D. Fernandes GFS, et al. Among authors: castagnolo d. RSC Med Chem. 2023 Feb 8;14(5):823-847. doi: 10.1039/d2md00415a. eCollection 2023 May 25. RSC Med Chem. 2023. PMID: 37252095 Free PMC article. Review.
64 results