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Targeting aberrant replication and DNA repair events for treating breast cancers.
Rajamanickam S, Park JH, Subbarayalu P, Timilsina S, Bates K, Yadav P, Nirzhor SSR, Eedunuri V, Mohammad TA, Jung KH, Onyeagucha B, Abdelfattah N, Benevides R, Lee G, Chen Y, Vadlamudi R, Brenner A, Kaklamani V, Jatoi I, Kuhn J, Hromas R, Gupta YK, Kaipparettu BA, Arbiser JL, Rao MK. Rajamanickam S, et al. Among authors: onyeagucha b. Commun Biol. 2022 May 24;5(1):493. doi: 10.1038/s42003-022-03413-w. Commun Biol. 2022. PMID: 35610507 Free PMC article.
Inhibition of FoxM1-Mediated DNA Repair by Imipramine Blue Suppresses Breast Cancer Growth and Metastasis.
Rajamanickam S, Panneerdoss S, Gorthi A, Timilsina S, Onyeagucha B, Kovalskyy D, Ivanov D, Hanes MA, Vadlamudi RK, Chen Y, Bishop AJ, Arbiser JL, Rao MK. Rajamanickam S, et al. Among authors: onyeagucha b. Clin Cancer Res. 2016 Jul 15;22(14):3524-36. doi: 10.1158/1078-0432.CCR-15-2535. Epub 2016 Feb 29. Clin Cancer Res. 2016. PMID: 26927663 Free PMC article.
Cross-talk among writers, readers, and erasers of m6A regulates cancer growth and progression.
Panneerdoss S, Eedunuri VK, Yadav P, Timilsina S, Rajamanickam S, Viswanadhapalli S, Abdelfattah N, Onyeagucha BC, Cui X, Lai Z, Mohammad TA, Gupta YK, Huang TH, Huang Y, Chen Y, Rao MK. Panneerdoss S, et al. Among authors: onyeagucha bc. Sci Adv. 2018 Oct 3;4(10):eaar8263. doi: 10.1126/sciadv.aar8263. eCollection 2018 Oct. Sci Adv. 2018. PMID: 30306128 Free PMC article.
Novel post-transcriptional and post-translational regulation of pro-apoptotic protein BOK and anti-apoptotic protein Mcl-1 determine the fate of breast cancer cells to survive or die.
Onyeagucha B, Subbarayalu P, Abdelfattah N, Rajamanickam S, Timilsina S, Guzman R, Zeballos C, Eedunuri V, Bansal S, Mohammad T, Chen Y, Vadlamudi RK, Rao MK. Onyeagucha B, et al. Oncotarget. 2017 Sep 12;8(49):85984-85996. doi: 10.18632/oncotarget.20841. eCollection 2017 Oct 17. Oncotarget. 2017. PMID: 29156771 Free PMC article.