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Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9.
Akhmetov A, Laurent JM, Gollihar J, Gardner EC, Garge RK, Ellington AD, Kachroo AH, Marcotte EM. Akhmetov A, et al. Among authors: gardner ec. Bio Protoc. 2018 Mar 20;8(6):e2765. doi: 10.21769/BioProtoc.2765. Bio Protoc. 2018. PMID: 29770349 Free PMC article.
Reprogramming the brain with synthetic neurobiology.
Gardner E, Ellington A. Gardner E, et al. Curr Opin Biotechnol. 2019 Aug;58:37-44. doi: 10.1016/j.copbio.2018.10.013. Epub 2018 Nov 17. Curr Opin Biotechnol. 2019. PMID: 30458406 Review.
Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality.
Goike J, Hsieh CL, Horton A, Gardner EC, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Renberg R, Johanson MJ, Cardona JA, Segall-Shapiro T, Zhou L, Nissly RH, Gontu A, Byrom M, Maranhao AC, Battenhouse AM, Gejji V, Soto-Sierra L, Foster ER, Woodard SL, Nikolov ZL, Lavinder J, Voss WN, Annapareddy A, Ippolito GC, Ellington AD, Marcotte EM, Finkelstein IJ, Hughes RA, Musser JM, Kuchipudi SV, Kapur V, Georgiou G, Dye JM, Boutz DR, McLellan JS, Gollihar JD. Goike J, et al. Among authors: gardner ec. bioRxiv [Preprint]. 2021 Apr 9:2021.04.07.438849. doi: 10.1101/2021.04.07.438849. bioRxiv. 2021. PMID: 33851158 Free PMC article. Preprint.
Rapid characterization of spike variants via mammalian cell surface display.
Javanmardi K, Chou CW, Terrace CI, Annapareddy A, Kaoud TS, Guo Q, Lutgens J, Zorkic H, Horton AP, Gardner EC, Nguyen G, Boutz DR, Goike J, Voss WN, Kuo HC, Dalby KN, Gollihar JD, Finkelstein IJ. Javanmardi K, et al. Among authors: gardner ec. Mol Cell. 2021 Dec 16;81(24):5099-5111.e8. doi: 10.1016/j.molcel.2021.11.024. Mol Cell. 2021. PMID: 34919820 Free PMC article.
SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Goike J, Hsieh CL, Horton AP, Gardner EC, Zhou L, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Xie X, Xia H, Shi PY, Renberg R, Segall-Shapiro TH, Terrace CI, Wu W, Shroff R, Byrom M, Ellington AD, Marcotte EM, Musser JM, Kuchipudi SV, Kapur V, Georgiou G, Weaver SC, Dye JM, Boutz DR, McLellan JS, Gollihar JD. Goike J, et al. Among authors: gardner ec. Commun Biol. 2023 Dec 11;6(1):1250. doi: 10.1038/s42003-023-05649-6. Commun Biol. 2023. PMID: 38082099 Free PMC article.
Engineering a human P2X2 receptor with altered ligand selectivity in yeast.
Gardner EC, Tramont C, Bachanová P, Wang C, Do H, Boutz DR, Kar S, Zemelman BV, Gollihar JD, Ellington AD. Gardner EC, et al. J Biol Chem. 2024 Mar 29;300(5):107248. doi: 10.1016/j.jbc.2024.107248. Online ahead of print. J Biol Chem. 2024. PMID: 38556082 Free PMC article.
41 results