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Isolevuglandins disrupt PU.1-mediated C1q expression and promote autoimmunity and hypertension in systemic lupus erythematosus.
Patrick DM, de la Visitación N, Krishnan J, Chen W, Ormseth MJ, Stein CM, Davies SS, Amarnath V, Crofford LJ, Williams JM, Zhao S, Smart CD, Dikalov S, Dikalova A, Xiao L, Van Beusecum JP, Ao M, Fogo AB, Kirabo A, Harrison DG. Patrick DM, et al. Among authors: van beusecum jp. JCI Insight. 2022 Jul 8;7(13):e136678. doi: 10.1172/jci.insight.136678. JCI Insight. 2022. PMID: 35608913 Free PMC article.
Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide.
Loperena R, Van Beusecum JP, Itani HA, Engel N, Laroumanie F, Xiao L, Elijovich F, Laffer CL, Gnecco JS, Noonan J, Maffia P, Jasiewicz-Honkisz B, Czesnikiewicz-Guzik M, Mikolajczyk T, Sliwa T, Dikalov S, Weyand CM, Guzik TJ, Harrison DG. Loperena R, et al. Among authors: van beusecum jp. Cardiovasc Res. 2018 Sep 1;114(11):1547-1563. doi: 10.1093/cvr/cvy112. Cardiovasc Res. 2018. PMID: 29800237 Free PMC article.
LNK deficiency promotes acute aortic dissection and rupture.
Laroumanie F, Korneva A, Bersi MR, Alexander MR, Xiao L, Zhong X, Van Beusecum JP, Chen Y, Saleh MA, McMaster WG, Gavulic KA, Dale BL, Zhao S, Guo Y, Shyr Y, Perrien DS, Cox NJ, Curci JA, Humphrey JD, Madhur MS. Laroumanie F, et al. Among authors: van beusecum jp. JCI Insight. 2018 Oct 18;3(20):e122558. doi: 10.1172/jci.insight.122558. JCI Insight. 2018. PMID: 30333305 Free PMC article.
Critical role of Interleukin 21 and T follicular helper cells in hypertension and vascular dysfunction.
Dale BL, Pandey AK, Chen Y, Smart CD, Laroumanie F, Ao M, Xiao L, Dikalova AE, Dikalov SI, Elijovich F, Foss JD, Barbaro NR, Van Beusecum JP, Deger SM, Alsouqi A, Itani HA, Norlander AE, Alexander MR, Zhao S, Ikizler TA, Algood HMS, Madhur MS. Dale BL, et al. Among authors: van beusecum jp. JCI Insight. 2019 Apr 23;5(11):e129278. doi: 10.1172/jci.insight.129278. JCI Insight. 2019. PMID: 31013256 Free PMC article.
High dietary salt-induced dendritic cell activation underlies microbial dysbiosis-associated hypertension.
Ferguson JF, Aden LA, Barbaro NR, Van Beusecum JP, Xiao L, Simmons AJ, Warden C, Pasic L, Himmel LE, Washington MK, Revetta FL, Zhao S, Kumaresan S, Scholz MB, Tang Z, Chen G, Reilly MP, Kirabo A. Ferguson JF, et al. Among authors: van beusecum jp. JCI Insight. 2019 Jun 4;5(13):e126241. doi: 10.1172/jci.insight.126241. JCI Insight. 2019. PMID: 31162138 Free PMC article.
ENaC in Salt-Sensitive Hypertension: Kidney and Beyond.
Pitzer AL, Van Beusecum JP, Kleyman TR, Kirabo A. Pitzer AL, et al. Among authors: van beusecum jp. Curr Hypertens Rep. 2020 Aug 27;22(9):69. doi: 10.1007/s11906-020-01067-9. Curr Hypertens Rep. 2020. PMID: 32852643 Free PMC article. Review.
32 results