Alexander-Katz A - Search Results

1

STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity.

Dane EL, Belessiotis-Richards A, Backlund C, Wang J, Hidaka K, Milling LE, Bhagchandani S, Melo MB, Wu S, Li N, Donahue N, Ni K, Ma L, Okaniwa M, Stevens MM, Alexander-Katz A, Irvine DJ. Dane EL, et al. Nat Mater. 2022 Jun;21(6):710-720. doi: 10.1038/s41563-022-01251-z. Epub 2022 May 23. Nat Mater. 2022. PMID: 35606429 Free PMC article.

2

Effect of particle diameter and surface composition on the spontaneous fusion of monolayer-protected gold nanoparticles with lipid bilayers.

Van Lehn RC, Atukorale PU, Carney RP, Yang YS, Stellacci F, Irvine DJ, Alexander-Katz A. Van Lehn RC, et al. Nano Lett. 2013 Sep 11;13(9):4060-7. doi: 10.1021/nl401365n. Epub 2013 Aug 20. Nano Lett. 2013. PMID: 23915118 Free PMC article.

3

Structure-Property Relationships of Amphiphilic Nanoparticles That Penetrate or Fuse Lipid Membranes.

Atukorale PU, Guven ZP, Bekdemir A, Carney RP, Van Lehn RC, Yun DS, Jacob Silva PH, Demurtas D, Yang YS, Alexander-Katz A, Stellacci F, Irvine DJ. Atukorale PU, et al. Bioconjug Chem. 2018 Apr 18;29(4):1131-1140. doi: 10.1021/acs.bioconjchem.7b00777. Epub 2018 Feb 27. Bioconjug Chem. 2018. PMID: 29465986 Free PMC article.

4

Single-Nanometer Changes in Nanopore Geometry Influence Curvature, Local Properties, and Protein Localization in Membrane Simulations.

Belessiotis-Richards A, Higgins SG, Butterworth B, Stevens MM, Alexander-Katz A. Belessiotis-Richards A, et al. Nano Lett. 2019 Jul 10;19(7):4770-4778. doi: 10.1021/acs.nanolett.9b01990. Epub 2019 Jun 26. Nano Lett. 2019. PMID: 31241342 Free article.

5

Calcium-triggered fusion of lipid membranes is enabled by amphiphilic nanoparticles.

Tahir MA, Guven ZP, Arriaga LR, Tinao B, Yang YS, Bekdemir A, Martin JT, Bhanji AN, Irvine D, Stellacci F, Alexander-Katz A. Tahir MA, et al. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18470-18476. doi: 10.1073/pnas.1902597117. Epub 2020 Jul 20. Proc Natl Acad Sci U S A. 2020. PMID: 32690682 Free PMC article.

6

Coarse-Grained Simulations Suggest the Epsin N-Terminal Homology Domain Can Sense Membrane Curvature without Its Terminal Amphipathic Helix.

Belessiotis-Richards A, Higgins SG, Sansom MSP, Alexander-Katz A, Stevens MM. Belessiotis-Richards A, et al. ACS Nano. 2020 Dec 22;14(12):16919-16928. doi: 10.1021/acsnano.0c05960. Epub 2020 Dec 10. ACS Nano. 2020. PMID: 33300799 Free PMC article.

7

Coarse-Grained Simulations Suggest Potential Competing Roles of Phosphoinositides and Amphipathic Helix Structures in Membrane Curvature Sensing of the AP180 N-Terminal Homology Domain.

Belessiotis-Richards A, Larsen AH, Higgins SG, Stevens MM, Alexander-Katz A. Belessiotis-Richards A, et al. J Phys Chem B. 2022 Apr 21;126(15):2789-2797. doi: 10.1021/acs.jpcb.2c00239. Epub 2022 Apr 8. J Phys Chem B. 2022. PMID: 35394774 Free PMC article.

8

Energy landscape for the insertion of amphiphilic nanoparticles into lipid membranes: A computational study.

Van Lehn RC, Alexander-Katz A. Van Lehn RC, et al. PLoS One. 2019 Jan 9;14(1):e0209492. doi: 10.1371/journal.pone.0209492. eCollection 2019. PLoS One. 2019. PMID: 30625163 Free PMC article.

9

Understanding the synergistic effect of physicochemical properties of nanoparticles and their cellular entry pathways.

Lin J, Miao L, Zhong G, Lin CH, Dargazangy R, Alexander-Katz A. Lin J, et al. Commun Biol. 2020 Apr 30;3(1):205. doi: 10.1038/s42003-020-0917-1. Commun Biol. 2020. PMID: 32355216 Free PMC article.

10

Population-based heteropolymer design to mimic protein mixtures.

Ruan Z, Li S, Grigoropoulos A, Amiri H, Hilburg SL, Chen H, Jayapurna I, Jiang T, Gu Z, Alexander-Katz A, Bustamante C, Huang H, Xu T. Ruan Z, et al. Among authors: alexander katz a. Nature. 2023 Mar;615(7951):251-258. doi: 10.1038/s41586-022-05675-0. Epub 2023 Mar 8. Nature. 2023. PMID: 36890370 Free PMC article.

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