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Response to supraphysiological testosterone is predicted by a distinct androgen receptor cistrome.
Qiu X, Brown LG, Conner JL, Nguyen HM, Boufaied N, Abou Alaiwi S, Seo JH, El Zarif T, Bell C, O'Connor E, Hanratty B, Pomerantz M, Freedman ML, Brown M, Haffner MC, Nelson PS, Feng FY, Labbé DP, Long HW, Corey E. Qiu X, et al. Among authors: brown lg, brown m. JCI Insight. 2022 May 23;7(10):e157164. doi: 10.1172/jci.insight.157164. JCI Insight. 2022. PMID: 35603787 Free PMC article.
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer.
Wang Q, Li W, Zhang Y, Yuan X, Xu K, Yu J, Chen Z, Beroukhim R, Wang H, Lupien M, Wu T, Regan MM, Meyer CA, Carroll JS, Manrai AK, Jänne OA, Balk SP, Mehra R, Han B, Chinnaiyan AM, Rubin MA, True L, Fiorentino M, Fiore C, Loda M, Kantoff PW, Liu XS, Brown M. Wang Q, et al. Among authors: brown m. Cell. 2009 Jul 23;138(2):245-56. doi: 10.1016/j.cell.2009.04.056. Cell. 2009. PMID: 19632176 Free PMC article.
8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC.
Ahmadiyeh N, Pomerantz MM, Grisanzio C, Herman P, Jia L, Almendro V, He HH, Brown M, Liu XS, Davis M, Caswell JL, Beckwith CA, Hills A, Macconaill L, Coetzee GA, Regan MM, Freedman ML. Ahmadiyeh N, et al. Among authors: brown m. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9742-6. doi: 10.1073/pnas.0910668107. Epub 2010 May 7. Proc Natl Acad Sci U S A. 2010. PMID: 20453196 Free PMC article.
SLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer.
Yang M, Xie W, Mostaghel E, Nakabayashi M, Werner L, Sun T, Pomerantz M, Freedman M, Ross R, Regan M, Sharifi N, Figg WD, Balk S, Brown M, Taplin ME, Oh WK, Lee GS, Kantoff PW. Yang M, et al. Among authors: brown m. J Clin Oncol. 2011 Jun 20;29(18):2565-73. doi: 10.1200/JCO.2010.31.2405. Epub 2011 May 23. J Clin Oncol. 2011. PMID: 21606417 Free PMC article.
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